Immunogenicity 13427

summary
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DUX4L8
Transcript ID
uc031sid.1
HLA INFO
A*01:01
TCR INFO

No TCR info found!

T cell Tumor cell A*01:01
sequence
Full length protein sequence (424 aa)
MALPT
1
PSDST
6
LPAEA
11
RGRGR
16
RRRLV
21
WTPSQ
26
SEALR
31
ACFER
36
NPYPG
41
IATRE
46
RLAQA
51
IGIPE
56
PRVQI
61
WFQNE
66
RSRQL
71
RQHRR
76
ESRPW
81
PGRRG
86
PPEGR
91
RKRTA
96
VTGSQ
101
TALLL
106
RAFEK
111
DRFPG
116
IAARE
121
ELARE
126
TGLPE
131
SRIQI
136
WFQNR
141
RARHP
146
GQGGR
151
APAQA
156
GGLCS
161
AAPGG
166
GHPAP
171
SWVAF
176
AHTGE
181
WGTGL
186
PAPHV
191
PCAPG
196
ALPQG
201
AFVSQ
206
AARAA
211
PALQP
216
SQAAT
221
AEGVS
226
QPAPA
231
RGDFA
236
YAAPA
241
PPDGA
246
LSHPQ
251
APRWP
256
PHPGK
261
SREDR
266
DPQRD
271
GLPGP
276
CAVAQ
281
PGPAQ
286
AGPQG
291
QGVLA
296
PPTSQ
301
GSPWW
306
GWGRG
311
PQVAG
316
AAWEP
321
QAGAA
326
PPPQP
331
APPDA
336
SASAR
341
QGQMQ
346
GIPAP
351
SQALQ
356
EPAPW
361
SALPC
366
GLLLD
371
ELLAS
376
PEFLQ
381
QAQPL
386
LETEA
391
PGELE
396
ASEEA
401
ASLEA
406
PLSEE
411
EYRAL
416
LEEL
421
Mutation Information
DNA mutation:
None
Peptide Range:
228 ~ 252
Mut AA position:
240 (13 in Wild Type peptide)
Alignment
Wild Type:
"GVSQPAPARGDFAYAAPAPPDGALS
||||||||||||.||||||||||||
Mutant:
GVSQPAPARGDFPYAAPAPPDGALS"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay