Immunogenicity 15371

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
AEBP1 (FPKM: 37.33)
Transcript ID
ENST00000223357
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (1158 aa)
MAAVR
1
GAPLL
6
SCLLA
11
LLALC
16
PGGRP
21
QTVLT
26
DDEIE
31
EFLEG
36
FLSEL
41
EPEPR
46
EDDVE
51
APPPP
56
EPTPR
61
VRKAQ
66
AGGKP
71
GKRPG
76
TAAEV
81
PPEKT
86
KDKGK
91
KGKKD
96
KGPKV
101
PKESL
106
EGSPR
111
PPKKG
116
KEKPP
121
KATKK
126
PKEKP
131
PKATK
136
KPKEK
141
PPKAT
146
KKPKE
151
KPPKA
156
TKKPP
161
SGKRP
166
PILAP
171
SETLE
176
WPLPP
181
PPSPG
186
PEELP
191
QEGGA
196
PLSNN
201
WQNPG
206
EETHV
211
EAREH
216
QPEPE
221
EETEQ
226
PTLDY
231
NDQIE
236
REDYE
241
DFEYI
246
RRQKQ
251
PRPPP
256
SRRRR
261
PERVW
266
PEPPE
271
EKAPA
276
PAPEE
281
RIEPP
286
VKPLL
291
PPLPP
296
DYGDG
301
YVIPN
306
YDDMD
311
YYFGP
316
PPPQK
321
PDAER
326
QTDEE
331
KEELK
336
KPKKE
341
DSSPK
346
EETDK
351
WAVEK
356
GKDHK
361
EPRKG
366
EELEE
371
EWTPT
376
EKVKC
381
PPIGM
386
ESHRI
391
EDNQI
396
RASSM
401
LRHGL
406
GAQRG
411
RLNMQ
416
TGATE
421
DDYYD
426
GAWCA
431
EDDAR
436
TQWIE
441
VDTRR
446
TTRFT
451
GVITQ
456
GRDSS
461
IHDDF
466
VTTFF
471
VGFSN
476
DSQTW
481
VMYTN
486
GYEEM
491
TFHGN
496
VDKDT
501
PVLSE
506
LPEPV
511
VARFI
516
RIYPL
521
TWNGS
526
LCMRL
531
EVLGC
536
SVAPV
541
YSYYA
546
QNEVV
551
ATDDL
556
DFRHH
561
SYKDM
566
RQLMK
571
VVNEE
576
CPTIT
581
RTYSL
586
GKSSR
591
GLKIY
596
AMEIS
601
DNPGE
606
HELGE
611
PEFRY
616
TAGIH
621
GNEVL
626
GRELL
631
LLLMQ
636
YLCRE
641
YRDGN
646
PRVRS
651
LVQDT
656
RIHLV
661
PSLNP
666
DGYEV
671
AAQMG
676
SEFGN
681
WALGL
686
WTEEG
691
FDIFE
696
DFPDL
701
NSVLW
706
GAEER
711
KWVPY
716
RVPNN
721
NLPIP
726
ERYLS
731
PDATV
736
STEVR
741
AIIAW
746
MEKNP
751
FVLGA
756
NLNGG
761
ERLVS
766
YPYDM
771
ARTPT
776
QEQLL
781
AAAMA
786
AARGE
791
DEDEV
796
SEAQE
801
TPDHA
806
IFRWL
811
AISFA
816
SAHLT
821
LTEPY
826
RGGCQ
831
AQDYT
836
GGMGI
841
VNGAK
846
WNPRT
851
GTIND
856
FSYLH
861
TNCLE
866
LSFYL
871
GCDKF
876
PHESE
881
LPREW
886
ENNKE
891
ALLTF
896
MEQVH
901
RGIKG
906
VVTDE
911
QGIPI
916
ANATI
921
SVSGI
926
NHGVK
931
TASGG
936
DYWRI
941
LNPGE
946
YRVTA
951
HAEGY
956
TPSAK
961
TCNVD
966
YDIGA
971
TQCNF
976
ILARS
981
NWKRI
986
REIMA
991
MNGNR
996
PIPHI
1001
DPSRP
1006
MTPQQ
1011
RRLQQ
1016
RRLQH
1021
RLRLR
1026
AQMRL
1031
RRLNA
1036
TTTLG
1041
PHTVP
1046
PTLPP
1051
APATT
1056
LSTTI
1061
EPWGL
1066
IPPTT
1071
AGWEE
1076
SETET
1081
YTEVV
1086
TEFGT
1091
EVEPE
1096
FGTKV
1101
EPEFE
1106
TQLEP
1111
EFETQ
1116
LEPEF
1121
EEEEE
1126
EEKEE
1131
EIATG
1136
QAFPF
1141
TTVET
1146
YTVNF
1151
GDF
1156
Mutation Information
DNA mutation:
c.C1160G
Peptide Range:
375 ~ 399
Mut AA position:
387 (13 in Wild Type peptide)
Alignment
Wild Type:
"EEWTPTEKVKCPPIGMESHRIEDNQ
||||||||||||.||||||||||||
Mutant:
EEWTPTEKVKCPRIGMESHRIEDNQ"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) AEBP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay