Immunogenicity 10003

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
IGHMBP2
Transcript ID
ENST00000255078
HLA INFO
A*68:01
TCR INFO

No TCR info found!

T cell Tumor cell A*68:01
sequence
Full length protein sequence (993 aa)
MASAA
1
VESFV
6
TKQLD
11
LLELE
16
RDAEV
21
EERRS
26
WQENI
31
SLKEL
36
QSRGV
41
CLLKL
46
QVSSQ
51
RTGLY
56
GRLLV
61
TFEPR
66
RYGSA
71
AALPS
76
NSFTS
81
GDIVG
86
LYDAA
91
NEGSQ
96
LATGI
101
LTRVT
106
QKSVT
111
VAFDE
116
SHDFQ
121
LSLDR
126
ENSYR
131
LLKLA
136
NDVTY
141
RRLKK
146
ALIAL
151
KKYHS
156
GPASS
161
LIEVL
166
FGRSA
171
PSPAS
176
EIHPL
181
TFFNT
186
CLDTS
191
QKEAV
196
LFALS
201
QKELA
206
IIHGP
211
PGTGK
216
TTTVV
221
EIILQ
226
AVKQG
231
LKVLC
236
CAPSN
241
IAVDN
246
LVERL
251
ALCKQ
256
RILRL
261
GHPAR
266
LLESI
271
QQHSL
276
DAVLA
281
RSDSA
286
QIVAD
291
IRKDI
296
DQVFV
301
KNKKT
306
QDKRE
311
KSNFR
316
NEIKL
321
LRKEL
326
KEREE
331
AAMLE
336
SLTSA
341
NVVLA
346
TNTGA
351
SADGP
356
LKLLP
361
ESYFD
366
VVVID
371
ECAQA
376
LEASC
381
WIPLL
386
KARKC
391
ILAGD
396
HKQLP
401
PTTVS
406
HKAAL
411
AGLSL
416
SLMER
421
LAEEY
426
GARVV
431
RTLTV
436
QYRMH
441
QAIMR
446
WASDT
451
MYLGQ
456
LTAHS
461
SVARH
466
LLRDL
471
PGVAA
476
TEETG
481
VPLLL
486
VDTAG
491
CGLFE
496
LEEED
501
EQSKG
506
NPGEV
511
RLVSL
516
HIQAL
521
VDAGV
526
PARDI
531
AVVSP
536
YNLQV
541
DLLRQ
546
SLVHR
551
HPELE
556
IKSVD
561
GFQGR
566
EKEAV
571
ILSFV
576
RSNRK
581
GEVGF
586
LAEDR
591
RINVA
596
VTRAR
601
RHVAV
606
ICDSR
611
TVNNH
616
AFLKT
621
LVEYF
626
TQHGE
631
VRTAF
636
EYLDD
641
IVPEN
646
YSHEN
651
SQGSS
656
HAATK
661
PQGPA
666
TSTRT
671
GSQRQ
676
EGGQE
681
AAAPA
686
RQGRK
691
KPAGK
696
SLASE
701
APSQP
706
SLNGG
711
SPEGV
716
ESQDG
721
VDHFR
726
AMIVE
731
FMASK
736
KMQLE
741
FPPSL
746
NSHDR
751
LRVHQ
756
IAEEH
761
GLRHD
766
SSGEG
771
KRRFI
776
TVSKR
781
APRPR
786
AALGP
791
PAGTG
796
GPAPL
801
QPVPP
806
TPAQT
811
EQPPR
816
EQRGP
821
DQPDL
826
RTLHL
831
ERLQR
836
VRSAQ
841
GQPAS
846
KEQQA
851
SGQQK
856
LPEKK
861
KKKAK
866
GHPAT
871
DLPTE
876
EDFEA
881
LVSAA
886
VKADN
891
TCGFA
896
KCTAG
901
VTTLG
906
QFCQL
911
CSRRY
916
CLSHH
921
LPEIH
926
GCGER
931
ARAHA
936
RQRIS
941
REGVL
946
YAGSG
951
TKNGS
956
LDPAK
961
RAQLQ
966
RRLDK
971
KLSEL
976
SNQRT
981
SRRKE
986
RGT
991
Mutation Information
DNA mutation:
None
Peptide Range:
333 ~ 357
Mut AA position:
345 (13 in Wild Type peptide)
Alignment
Wild Type:
"REEAAMLESLTSANVVLATNTGASA
||||||||||||.||||||||||||
Mutant:
REEAAMLESLTSTNVVLATNTGASA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) IGHMBP2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay