Immunogenicity 10018

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
DUX4L4
Transcript ID
ENST00000538692
HLA INFO
DQA*01:03 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:02
sequence
Full length protein sequence (483 aa)
MKGWS
1
LPACG
6
PLQGR
11
LAGWL
16
AVRAG
21
LLAAP
26
AAVHS
31
PAEVH
36
GSPPA
41
SLCPR
46
PSVKF
51
RPGLT
56
AMALP
61
TPSDS
66
TLPAE
71
ARGRG
76
RRRRL
81
VWTPS
86
QSEAL
91
RACFE
96
RNPYP
101
GIATR
106
ERLAQ
111
AIGIP
116
EPRVQ
121
IWFQN
126
ERSRQ
131
LRQHR
136
RESRP
141
WPGRR
146
GPPEG
151
RRKRT
156
AVTGS
161
QTALL
166
LRAFE
171
KDRFP
176
GIAAR
181
EELAR
186
ETGLP
191
ESRIQ
196
IWFQN
201
RRARH
206
PGQGG
211
RAPAQ
216
AGGLC
221
SAAPG
226
GGHPA
231
PSWVA
236
FAHTG
241
AWGTG
246
LPAPH
251
VPCAP
256
GALPQ
261
GAFVS
266
QAARA
271
APALQ
276
PSQAA
281
PAEGV
286
SQPAP
291
ARGDF
296
AYAAP
301
APPDG
306
ALSHP
311
QAPRW
316
PPHPG
321
KSRED
326
RDPQR
331
DGLPG
336
PCAVA
341
QPGPA
346
QAGPQ
351
GQGVL
356
APPTS
361
QGSPW
366
WGWGR
371
GPQVA
376
GAAWE
381
PQAGE
386
APPPQ
391
PAPPD
396
ASARQ
401
GQMQG
406
IPAPS
411
QALQE
416
PAPWS
421
ALPCG
426
LLLDE
431
LLASP
436
EFLQQ
441
AQPLL
446
ETEAP
451
GELEA
456
SEEAA
461
SLEAP
466
LSEEE
471
YRALL
476
EEL
481
Mutation Information
DNA mutation:
None
Peptide Range:
366 ~ 390
Mut AA position:
378 (13 in Wild Type peptide)
Alignment
Wild Type:
"QGSPWWGWGRGPQVAGAAWEPQAGE
||||||||||||.||||||||||||
Mutant:
QGSPWWGWGRGPPVAGAAWEPQAGE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DUX4L4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay