Immunogenicity 10110

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
MTMR8
Transcript ID
ENST00000374852
HLA INFO
DRB*13:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*13:01
sequence
Full length protein sequence (704 aa)
MDHIT
1
VPKVE
6
NVKLV
11
DRYVS
16
KKPAN
21
GILYL
26
TATHL
31
IYVEA
36
SGAAR
41
KETWI
46
ALHHI
51
ATVEK
56
LPITS
61
LGCPL
66
TLRCK
71
NFRVA
76
HFVLD
81
SDLVC
86
HEVYI
91
SLLKL
96
SQPAL
101
PEDLY
106
AFSYN
111
PKSSK
116
EMRES
121
GWKLI
126
DPISD
131
FGRMG
136
IPNRN
141
WTITD
146
ANRNY
151
EICST
156
YPPEI
161
VVPKS
166
VTLGT
171
VVGSS
176
KFRSK
181
ERVPV
186
LSYLY
191
KENNA
196
AICRC
201
SQPLS
206
GFYTR
211
CVDDE
216
LLLEA
221
ISQTN
226
PGSQF
231
MYVVD
236
TRPKL
241
NAMAN
246
RAAGK
251
GYENE
256
DNYAN
261
IRFRF
266
MGIEN
271
IHVMR
276
SSLQK
281
LLEVC
286
ELKTP
291
TMSEF
296
LSGLE
301
SSGWL
306
RHIKA
311
IMDAG
316
IFITK
321
AVKVE
326
KASVL
331
VHCSD
336
GWDRT
341
AQVCS
346
VASIL
351
LDPFY
356
RTFKG
361
LMILI
366
EKEWI
371
SMGHK
376
FSQRC
381
GHLDG
386
DSKEV
391
SPIFT
396
QFLDC
401
IWQLM
406
EQFPC
411
AFEFN
416
ENFLL
421
EIHDH
426
VFSCQ
431
FGNFL
436
GNCQK
441
DREDL
446
RVYEK
451
THSVW
456
PFLVQ
461
RKPDF
466
RNPLY
471
KGFTM
476
YGVLN
481
PSTVP
486
YNIQF
491
WCGMY
496
NRFDK
501
GLQPK
506
QSMLE
511
SLLEI
516
KKQRA
521
MLETD
526
VHELE
531
KKLKV
536
RDEPP
541
EEICT
546
CSQLG
551
NILSQ
556
HLGSP
561
LTNPL
566
GFMGI
571
NGDLN
576
TLMEN
581
GTLSR
586
EGGLR
591
AQMDQ
596
VKSQG
601
ADLHH
606
NCCEI
611
VGSLR
616
AINIS
621
GDVGI
626
SEAMG
631
ISGDM
636
CTFEA
641
TGFSK
646
DLGIC
651
GAMDI
656
SEATG
661
ISGNL
666
GISEA
671
RGFSG
676
DMGIL
681
GDTGI
686
SKAST
691
KEADY
696
SKHQ
701
Mutation Information
DNA mutation:
None
Peptide Range:
418 ~ 442
Mut AA position:
430 (13 in Wild Type peptide)
Alignment
Wild Type:
"EFNENFLLEIHDHVFSCQFGNFLGN
||||||||||||.||||||||||||
Mutant:
EFNENFLLEIHDYVFSCQFGNFLGN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MTMR8

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay