Immunogenicity 10169

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
MTREX
Transcript ID
ENST00000545714
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (941 aa)
MEGAS
1
RVCRQ
6
GRVAL
11
PAEED
16
YLPLK
21
PRVGK
26
AAKEY
31
PFILD
36
AFQRE
41
AIQCV
46
DNNQS
51
VLVSA
56
HTSAG
61
KTVCA
66
EYAIA
71
LALRE
76
KQRVI
81
FTSPI
86
KALSN
91
QKYRE
96
MYEEF
101
QDVGL
106
MTGDV
111
TINPT
116
ASCLV
121
MTTEI
126
LRSML
131
YRGSE
136
VMREV
141
AWVIF
146
DEIHY
151
MRDSE
156
RGVVW
161
EETII
166
LLPDN
171
VHYVF
176
LSATI
181
PNARQ
186
FAEWI
191
CHLHK
196
QPCHV
201
IYTDY
206
RPTPL
211
QHYIF
216
PAGGD
221
GLHLV
226
VDENG
231
DFRED
236
NFNTA
241
MQVLR
246
DAGDL
251
AKGDQ
256
KGRKG
261
GTKGP
266
SNVFK
271
IVKMI
276
MERNF
281
QPVII
286
FSFSK
291
KDCEA
296
YALQM
301
TKLDF
306
NTDEE
311
KKMVE
316
EVFSN
321
AIDCL
326
SDEDK
331
KLPQV
336
EHVLP
341
LLKRG
346
IGIHH
351
GGLLP
356
ILKET
361
IEILF
366
SEGLI
371
KALFA
376
TETFA
381
MGINM
386
PARTV
391
LFTNA
396
RKFDG
401
KDFRW
406
ISSGE
411
YIQMS
416
GRAGR
421
RGMDD
426
RGIVI
431
LMVDE
436
KMSPT
441
IGKQL
446
LKGSA
451
DPLNS
456
AFHLT
461
YNMVL
466
NLLRV
471
EEINP
476
EYMLE
481
KSFYQ
486
FQHYR
491
AIPGV
496
VEKVK
501
NSEEQ
506
YNKIV
511
IPNEE
516
SVVIY
521
YKIRQ
526
QLAKL
531
GKEIE
536
EYIHK
541
PKYCL
546
PFLQP
551
GRLVK
556
VKNEG
561
DDFGW
566
GVVVN
571
FSKKS
576
NVKPN
581
SGELD
586
PLYVV
591
EVLLR
596
CSKES
601
LKNSA
606
TEAAK
611
PAKPD
616
EKGEM
621
QVVPV
626
LVHLL
631
SAISS
636
VRLYI
641
PKDLR
646
PVDNR
651
QSVLK
656
SIQEV
661
QKRFP
666
DGIPL
671
LDPID
676
DMGIQ
681
DQGLK
686
KVIQK
691
VEAFE
696
HRMYS
701
HPLHN
706
DPNLE
711
TVYTL
716
CEKKA
721
QIAID
726
IKSAK
731
RELKK
736
ARTVL
741
QMDEL
746
KCRKR
751
VLRRL
756
GFATS
761
SDVIE
766
MKGRV
771
ACEIS
776
SADEL
781
LLTEM
786
MFNGL
791
FNDLS
796
AEQAT
801
ALLSC
806
FVFQE
811
NSSEM
816
PKLTE
821
QLAGP
826
LRQMQ
831
ECAKR
836
IAKVS
841
AEAKL
846
EIDEE
851
TYLSS
856
FKPHL
861
MDVVY
866
TWATG
871
ATFAH
876
ICKMT
881
DVFEG
886
SIIRC
891
MRRLE
896
ELLRQ
901
MCQAA
906
KAIGN
911
TELEN
916
KFAEG
921
ITKIK
926
RDIVF
931
AASLY
936
L
941
Mutation Information
DNA mutation:
None
Peptide Range:
372 ~ 396
Mut AA position:
384 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGLIKALFATETFAMGINMPARTVL
||||||||||||.||||||||||||
Mutant:
EGLIKALFATETCAMGINMPARTVL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SKIV2L2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay