Immunogenicity 10287

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
PRKCB
Transcript ID
ENST00000303531
HLA INFO
DQA*02:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*06:03
sequence
Full length protein sequence (673 aa)
MADPA
1
AGPPP
6
SEGEE
11
STVRF
16
ARKGA
21
LRQKN
26
VHEVK
31
NHKFT
36
ARFFK
41
QPTFC
46
SHCTD
51
FIWGF
56
GKQGF
61
QCQVC
66
CFVVH
71
KRCHE
76
FVTFS
81
CPGAD
86
KGPAS
91
DDPRS
96
KHKFK
101
IHTYS
106
SPTFC
111
DHCGS
116
LLYGL
121
IHQGM
126
KCDTC
131
MMNVH
136
KRCVM
141
NVPSL
146
CGTDH
151
TERRG
156
RIYIQ
161
AHIDR
166
DVLIV
171
LVRDA
176
KNLVP
181
MDPNG
186
LSDPY
191
VKLKL
196
IPDPK
201
SESKQ
206
KTKTI
211
KCSLN
216
PEWNE
221
TFRFQ
226
LKESD
231
KDRRL
236
SVEIW
241
DWDLT
246
SRNDF
251
MGSLS
256
FGISE
261
LQKAS
266
VDGWF
271
KLLSQ
276
EEGEY
281
FNVPV
286
PPEGS
291
EANEE
296
LRQKF
301
ERAKI
306
SQGTK
311
VPEEK
316
TTNTV
321
SKFDN
326
NGNRD
331
RMKLT
336
DFNFL
341
MVLGK
346
GSFGK
351
VMLSE
356
RKGTD
361
ELYAV
366
KILKK
371
DVVIQ
376
DDDVE
381
CTMVE
386
KRVLA
391
LPGKP
396
PFLTQ
401
LHSCF
406
QTMDR
411
LYFVM
416
EYVNG
421
GDLMY
426
HIQQV
431
GRFKE
436
PHAVF
441
YAAEI
446
AIGLF
451
FLQSK
456
GIIYR
461
DLKLD
466
NVMLD
471
SEGHI
476
KIADF
481
GMCKE
486
NIWDG
491
VTTKT
496
FCGTP
501
DYIAP
506
EIIAY
511
QPYGK
516
SVDWW
521
AFGVL
526
LYEML
531
AGQAP
536
FEGED
541
EDELF
546
QSIME
551
HNVAY
556
PKSMS
561
KEAVA
566
ICKGL
571
MTKHP
576
GKRLG
581
CGPEG
586
ERDIK
591
EHAFF
596
RYIDW
601
EKLER
606
KEIQP
611
PYKPK
616
ACGRN
621
AENFD
626
RFFTR
631
HPPVL
636
TPPDQ
641
EVIRN
646
IDQSE
651
FEGFS
656
FVNSE
661
FLKPE
666
VKS
671
Mutation Information
DNA mutation:
None
Peptide Range:
36 ~ 60
Mut AA position:
48 (13 in Wild Type peptide)
Alignment
Wild Type:
"NHKFTARFFKQPTFCSHCTDFIWGF
||||||||||||.||||||||||||
Mutant:
NHKFTARFFKQPAFCSHCTDFIWGF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRKCB

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay