Immunogenicity 10453

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
TJP3
Transcript ID
uc010xhw.3
HLA INFO
A*68:01
TCR INFO

No TCR info found!

T cell Tumor cell A*68:01
sequence
Full length protein sequence (919 aa)
MEELT
1
IWEQH
6
TATLS
11
KDPRR
16
GFGIA
21
ISGGR
26
DRPGG
31
SMVVS
36
DVVPG
41
GPAEG
46
RLQTG
51
DHIVM
56
VNGVS
61
MENAT
66
SAFAI
71
QILKT
76
CTKMA
81
NITVK
86
RPRRI
91
HLPAT
96
KASPS
101
SPGRQ
106
DSDED
111
DGPQR
116
VEEVD
121
QGRGY
126
DGDSS
131
SGSGR
136
SWDER
141
SRRPR
146
PGRRG
151
RAGSH
156
GRRSP
161
GGGSE
166
ANGLA
171
LVSGF
176
KRLPR
181
QDVQM
186
KPVKS
191
VLVKR
196
RDSEE
201
FGVKL
206
GSQIF
211
IKHIT
216
DSGLA
221
ARHRG
226
LQEGD
231
LILQI
236
NGVSS
241
QNLSL
246
NDTRR
251
LIEKS
256
EGKLS
261
LLVLR
266
DRGQF
271
LVNIP
276
PAVSD
281
SDSSP
286
LEDIS
291
DLASE
296
LSQAP
301
PSHIP
306
PPPRH
311
AQRSP
316
EASQT
321
DSPVE
326
SPRLR
331
RESSV
336
DSRTI
341
SEPDE
346
QRSEL
351
PRESS
356
YDIYR
361
VPSSQ
366
SMEDR
371
GYSPD
376
TRVVR
381
FLKGK
386
SIGLR
391
LAGGN
396
DVGIF
401
VSGVQ
406
AGSPA
411
DGQGI
416
QEGDQ
421
ILQVN
426
DVPFQ
431
NLTRE
436
EAVQF
441
LLGLP
446
PGEEM
451
ELVTQ
456
RKQDI
461
FWKMV
466
QSRVG
471
DSFYI
476
RTHFE
481
LEPSP
486
PSGLG
491
FTRGD
496
VFHVL
501
DTLHP
506
GPGQS
511
HARGG
516
HWLAV
521
RMGRD
526
LREQE
531
RGIIP
536
NQSRA
541
EQLAS
546
LEAAQ
551
RAVGV
556
GPGSS
561
AGSNA
566
RAEFW
571
RLRGL
576
RRGAK
581
KTTQR
586
SREDL
591
SALTR
596
QGRYP
601
PYERV
606
VLREA
611
SFKRP
616
VVILG
621
PVADI
626
AMQKL
631
TAEMP
636
DQFEI
641
AETVS
646
RTDSP
651
SKIIK
656
LDTVR
661
VIAEK
666
DKHAL
671
LDVTP
676
SAIER
681
LNYVQ
686
YYPIV
691
VFFIP
696
ESRPA
701
LKALR
706
QWLAP
711
ASRRS
716
TRRLY
721
AQAQK
726
LRKHS
731
SHLFT
736
ATIPL
741
NGTSD
746
TWYQE
751
LKAII
756
REQQT
761
RPIWT
766
AEDQL
771
DGSLE
776
DNLDL
781
PHHGL
786
ADSSA
791
DLSCD
796
SRVNS
801
DYETD
806
GEGGA
811
YTDGE
816
GYTDG
821
EGGPY
826
TDVDD
831
EPPAP
836
ALARS
841
SEPVQ
846
ADESQ
851
SPRDR
856
GRISA
861
HQGAQ
866
VDSRH
871
PQGQW
876
RQDSM
881
RTYER
886
EALKK
891
KFMRV
896
HDAES
901
SDEDG
906
YDWGP
911
ATDL
916
Mutation Information
DNA mutation:
None
Peptide Range:
448 ~ 472
Mut AA position:
460 (13 in Wild Type peptide)
Alignment
Wild Type:
"GLPPGEEMELVTQRKQDIFWKMVQS
||||||||||||.||||||||||||
Mutant:
GLPPGEEMELVTERKQDIFWKMVQS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TJP3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay