Immunogenicity 7236
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HDAC9
Transcript ID
NM_178423
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1066 aa)
MHSMI
1
SSVDV
6
KSEVP
11
VGLEP
16
ISPLD
21
LRTDL
26
RMMMP
31
VVDPV
36
VREKQ
41
LQQEL
46
LLIQQ
51
QQQIQ
56
KQLLI
61
AEFQK
66
QHENL
71
TRQHQ
76
AQLQE
81
HIKEL
86
LAIKQ
91
QQELL
96
EKEQK
101
LEQQR
106
QEQEV
111
ERHRR
116
EQQLP
121
PLRGK
126
DRGRE
131
RAVAS
136
TEVKQ
141
KLQEF
146
LLSKS
151
ATKDT
156
PTNGK
161
NHSVS
166
RHPKL
171
WYTAA
176
HHTSL
181
DQSSP
186
PLSGT
191
SPSYK
196
YTLPG
201
AQDAK
206
DDFPL
211
RKTAS
216
EPNLK
221
VRSRL
226
KQKVA
231
ERRSS
236
PLLRR
241
KDGNV
246
VTSFK
251
KRMFE
256
VTESS
261
VSSSS
266
PGSGP
271
SSPNN
276
GPTGS
281
VTENE
286
TSVLP
291
PTPHA
296
EQMVS
301
QQRIL
306
IHEDS
311
MNLLS
316
LYTSP
321
SLPNI
326
TLGLP
331
AVPSQ
336
LNASN
341
SLKEK
346
QKCET
351
QTLRQ
356
GVPLP
361
GQYGG
366
SIPAS
371
SSHPH
376
VTLEG
381
KPPNS
386
SHQAL
391
LQHLL
396
LKEQM
401
RQQKL
406
LVAGG
411
VPLHP
416
QSPLA
421
TKERI
426
SPGIR
431
GTHKL
436
PRHRP
441
LNRTQ
446
SAPLP
451
QSTLA
456
QLVIQ
461
QQHQQ
466
FLEKQ
471
KQYQQ
476
QIHMN
481
KLLSK
486
SIEQL
491
KQPGS
496
HLEEA
501
EEELQ
506
GDQAM
511
QEDRA
516
PSSGN
521
STRSD
526
SSACV
531
DDTLG
536
QVGAV
541
KVKEE
546
PVDSD
551
EDAQI
556
QEMES
561
GEQAA
566
FMQQP
571
FLEPT
576
HTRAL
581
SVRQA
586
PLAAV
591
GMDGL
596
EKHRL
601
VSRTH
606
SSPAA
611
SVLPH
616
PAMDR
621
PLQPG
626
SATGI
631
AYDPL
636
MLKHQ
641
CVCGN
646
STTHP
651
EHAGR
656
IQSIW
661
SRLQE
666
TGLLN
671
KCERI
676
QGRKA
681
SLEEI
686
QLVHS
691
EHHSL
696
LYGTN
701
PLDGQ
706
KLDPR
711
ILLGD
716
DSQKF
721
FSSLP
726
CGGLG
731
VDSDT
736
IWNEL
741
HSSGA
746
ARMAV
751
GCVIE
756
LASKV
761
ASGEL
766
KNGFA
771
VVRPP
776
GHHAE
781
ESTAM
786
GFCFF
791
NSVAI
796
TAKYL
801
RDQLN
806
ISKIL
811
IVDLD
816
VHHGN
821
GTQQA
826
FYADP
831
SILYI
836
SLHRY
841
DEGNF
846
FPGSG
851
APNEV
856
GTGLG
861
EGYNI
866
NIAWT
871
GGLDP
876
PMGDV
881
EYLEA
886
FRTIV
891
KPVAK
896
EFDPD
901
MVLVS
906
AGFDA
911
LEGHT
916
PPLGG
921
YKVTA
926
KCFGH
931
LTKQL
936
MTLAD
941
GRVVL
946
ALEGG
951
HDLTA
956
ICDAS
961
EACVN
966
ALLGN
971
ELEPL
976
AEDIL
981
HQSPN
986
MNAVI
991
SLQKI
996
IEIQS
1001
KYWKS
1006
VRMVA
1011
VPRGC
1016
ALAGA
1021
QLQEE
1026
TETVS
1031
ALASL
1036
TVDVE
1041
QPFAQ
1046
EDSRT
1051
AGEPM
1056
EEEPA
1061
L
1066
Mutation Information
DNA mutation:
None
Peptide Range:
917 ~ 941
Mut AA position:
929 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGHTPPLGGYKVTAKCFGHLTKQLM
||||||||||||.||||||||||||
Mutant:
EGHTPPLGGYKVMAKCFGHLTKQLM"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) HDAC9
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay