Immunogenicity 8305

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
SGSM1
Transcript ID
NM_001039948
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (1148 aa)
MASAP
1
AEAET
6
RQRLL
11
RTVKK
16
EVKQI
21
MEEAV
26
TRKFV
31
HEDSS
36
HIISF
41
CAAVE
46
ACVLH
51
GLRRR
56
AAGFL
61
RSNKI
66
AALFM
71
KVGKN
76
FPPAE
81
DLSRK
86
VQDLE
91
QLIES
96
ARNQI
101
QGLQE
106
NVRKL
111
PKLPN
116
LSPLA
121
IKHLW
126
IRTAL
131
FEKVL
136
DKIVH
141
YLVEN
146
SSKYY
151
EKEAL
156
LMDPV
161
DGPIL
166
ASLLV
171
GPCAL
176
EYTKM
181
KTADH
186
FWTDP
191
SADEL
196
VQRHR
201
IHSSH
206
VRQDS
211
PTKRP
216
ALCIQ
221
KRHSS
226
GSMDD
231
RPSLS
236
ARDYV
241
ESLHQ
246
NSRAT
251
LLYGK
256
NNVLV
261
QPRDD
266
MEAVP
271
GYLSL
276
HQTAD
281
VMTLK
286
WTPNQ
291
LMNGS
296
VGDLD
301
YEKSV
306
YWDYA
311
MTIRL
316
EEIVY
321
LHCHQ
326
QVDSG
331
GTVVL
336
VSQDG
341
IQRPP
346
FRFPK
351
GGHLL
356
QFLSC
361
LENGL
366
LPHGQ
371
LDPPL
376
WSQRG
381
KGKVF
386
PKLRK
391
RSPQG
396
SAEST
401
SSDKD
406
DDEAT
411
DYVFR
416
IIYPG
421
MQSEF
426
VAPDF
431
LGSTS
436
SVSVG
441
PAWMM
446
VPAGR
451
SMLVV
456
ARGSQ
461
WEPAR
466
WDTTL
471
PTPSP
476
KEQPP
481
MPQDL
486
MDVSV
491
SNLPS
496
LWQPS
501
PRKSS
506
CSSCS
511
QSGSA
516
DGSST
521
NGCNH
526
ERAPL
531
KLLCD
536
NMKYQ
541
ILSRA
546
FYGWL
551
AYCRH
556
LSTVR
561
THLSA
566
LVNHM
571
IVSPD
576
LPCDA
581
GQGLT
586
ARIWE
591
QYLHD
596
STSYE
601
EQELL
606
RLIYY
611
GGIQP
616
EIRKA
621
VWPFL
626
LGHYQ
631
FGMTE
636
TERKE
641
VDEQI
646
HACYA
651
QTMAE
656
WLGCE
661
AIVRQ
666
RERES
671
HAAAL
676
AKCSS
681
GASLD
686
SHLHR
691
MLHRD
696
STISN
701
ESSQS
706
CSSGR
711
QNIRL
716
HSDSS
721
SSTQV
726
FESVD
731
EVEQV
736
EAEGR
741
LEEKQ
746
PKIPN
751
GNLVN
756
GTCSP
761
DSGHP
766
SSHNF
771
SSGLS
776
EHSEP
781
SLSTE
786
DSVLD
791
AQRNT
796
PTVLR
801
PRDGS
806
VDDRQ
811
SSEAT
816
TSQDE
821
APREE
826
LAVQD
831
SLESD
836
LLANE
841
SMDEF
846
MSITG
851
SLDMA
856
LPEKD
861
DVVME
866
GWRSS
871
ETEKH
876
GQADS
881
EDNLS
886
EEPEM
891
ESLFP
896
ALASL
901
AVTTS
906
ANEVS
911
PVSSS
916
GVTYS
921
PELLD
926
LYTVN
931
LHRIE
936
KDVQR
941
CDRNY
946
WYFTP
951
ANLEK
956
LRNIM
961
CSYIW
966
QHIEI
971
GYVQG
976
MCDLL
981
APLLV
986
ILDDE
991
ALAFS
996
CFTEL
1001
MKRMN
1006
QNFPH
1011
GGAMD
1016
THFAN
1021
MRSLI
1026
QILDS
1031
ELFEL
1036
MHQNG
1041
DYTHF
1046
YFCYR
1051
WFLLD
1056
FKREL
1061
VYDDV
1066
FLVWE
1071
TIWAA
1076
KHVSS
1081
AHYVL
1086
FIALA
1091
LVEVY
1096
RDIIL
1101
ENNMD
1106
FTDII
1111
KFFNE
1116
MAERH
1121
NTKQV
1126
LKLAR
1131
DLVYK
1136
VQTLI
1141
ENK
1146
Mutation Information
DNA mutation:
None
Peptide Range:
327 ~ 351
Mut AA position:
339 (13 in Wild Type peptide)
Alignment
Wild Type:
"HCHQQVDSGGTVVLVSQDGIQRPPF
||||||||||||.||||||||||||
Mutant:
HCHQQVDSGGTVGLVSQDGIQRPPF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SGSM1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay