Immunogenicity 8331

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FAM160B2
Transcript ID
NM_022749
HLA INFO
DQA*02:01 / DQB*02:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:01
sequence
Full length protein sequence (743 aa)
MLSRL
1
GALLQ
6
EAVGA
11
REPSI
16
DLLQA
21
FVEHW
26
KGITH
31
YYIES
36
TDEST
41
PAKKT
46
DIPWR
51
LKQML
56
DILVY
61
EEQQQ
66
AAAGE
71
AGPCL
76
EYLLQ
81
HKILE
86
TLCTL
91
GKAEY
96
PPGMR
101
QQVFQ
106
FFSKV
111
LAQVQ
116
HPLLH
121
YLSVH
126
RPVQK
131
LLRLG
136
GTASG
141
SVTEK
146
EEVQF
151
TTVLC
156
SKIQQ
161
DPELL
166
AYILE
171
GKKIV
176
GRKKA
181
CGEPT
186
ALPKD
191
TTSHG
196
DKDCS
201
HDGAP
206
ARPQL
211
DGESC
216
GAQAL
221
NSHMP
226
AETEE
231
LDGGT
236
TESNL
241
ITSLL
246
GLCQS
251
KKSRV
256
ALKAQ
261
ENLLL
266
LVSMA
271
SPAAA
276
TYLVQ
281
SSACC
286
PAIVR
291
HLCQL
296
YRSMP
301
VFLDP
306
ADIAT
311
LEGIS
316
WRLPS
321
APSDE
326
ASFPG
331
KEALA
336
AFLGW
341
FDYCD
346
HLITE
351
AHTVV
356
ADALA
361
KAVAE
366
NFFVE
371
TLQPQ
376
LLHVS
381
EQSIL
386
TSTAL
391
LTAML
396
RQLRS
401
PALLR
406
EAVAF
411
LLGTD
416
RQPEA
421
PGDNP
426
HTLYA
431
HLIGH
436
CDHLS
441
DEISI
446
TTLRL
451
FEELL
456
QKPHE
461
GIIHS
466
LVLRN
471
LEGRP
476
YVAWG
481
SPEPE
486
SYEDT
491
LDLEE
496
DPYFT
501
DSFLD
506
SGFQT
511
PAKPR
516
LAPAT
521
SYDGK
526
TAVTE
531
IVNSF
536
LCLVP
541
EEAKT
546
SAFLE
551
ETGYD
556
TYVHD
561
AYGLF
566
QECSS
571
RVASW
576
GWPLT
581
PTPLD
586
PHEPE
591
RPFFE
596
GHFLR
601
VLFDR
606
MSRIL
611
DQPYS
616
LNLQV
621
TSVLS
626
RLALF
631
PHPHI
636
HEYLL
641
DPYIS
646
LAPGC
651
RSLFS
656
VLVRV
661
IGDLM
666
QRIQR
671
VPQFP
676
GKLLL
681
VRKQL
686
TGQAP
691
GEQLD
696
HQTLL
701
QGVVV
706
LEEFC
711
KELAA
716
IAFVK
721
FPPHD
726
PRQNV
731
SPAPE
736
GQV
741
Mutation Information
DNA mutation:
None
Peptide Range:
33 ~ 57
Mut AA position:
45 (13 in Wild Type peptide)
Alignment
Wild Type:
"ITHYYIESTDESTPAKKTDIPWRLK
||||||||||||.||||||||||||
Mutant:
ITHYYIESTDESPPAKKTDIPWRLK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM160B2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay