Immunogenicity 8337

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
FFAR3
Transcript ID
NM_005304
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (346 aa)
MDTGP
1
DQSYF
6
SGNHW
11
FVFSV
16
YLLTF
21
LVGLP
26
LNLLA
31
LVVFV
36
GKLQR
41
RPVAV
46
DVLLL
51
NLTAS
56
DLLLL
61
LFLPF
66
RMVEA
71
ANGMH
76
WPLPF
81
ILCPL
86
SGFIF
91
FTTIY
96
LTALF
101
LAAVS
106
IERFL
111
SVAHP
116
LWYKT
121
RPRLG
126
QAGLV
131
SVACW
136
LLASA
141
HCSVV
146
YVIEF
151
SGDIS
156
HSQGT
161
NGTCY
166
LEFRK
171
DQLAI
176
LLPVR
181
LEMAV
186
VLFVV
191
PLIIT
196
SYCYS
201
RLVWI
206
LGRGG
211
SHRRQ
216
RRVAG
221
LLAAT
226
LLNFL
231
VCFGP
236
YNVSH
241
VVGYI
246
CGESP
251
AWRIY
256
VTLLS
261
TLNSC
266
VDPFV
271
YYFSS
276
SGFQA
281
DFHEL
286
LRRLC
291
GLWGQ
296
WQQES
301
SMELK
306
EQKGG
311
EEQRA
316
DRPAE
321
RKTSE
326
HSQGC
331
GTGGQ
336
VACAE
341
S
346
Mutation Information
DNA mutation:
None
Peptide Range:
33 ~ 57
Mut AA position:
45 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLALVVFVGKLQRRPVAVDVLLLNL
||||||||||||.||||||||||||
Mutant:
LLALVVFVGKLQHRPVAVDVLLLNL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FFAR3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay