Immunogenicity 8852

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HLA-DRB5
Transcript ID
NM_002125
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (266 aa)
MVCLK
1
LPGGS
6
YMAKL
11
TVTLM
16
VLSSP
21
LALAG
26
DTRPR
31
FLQQD
36
KYECH
41
FFNGT
46
ERVRF
51
LHRDI
56
YNQEE
61
DLRFD
66
SDVGE
71
YRAVT
76
ELGRP
81
DAEYW
86
NSQKD
91
FLEDR
96
RAAVD
101
TYCRH
106
NYGVG
111
ESFTV
116
QRRVE
121
PKVTV
126
YPART
131
QTLQH
136
HNLLV
141
CSVNG
146
FYPGS
151
IEVRW
156
FRNSQ
161
EEKAG
166
VVSTG
171
LIQNG
176
DWTFQ
181
TLVML
186
ETVPR
191
SGEVY
196
TCQVE
201
HPSVT
206
SPLTV
211
EWRAQ
216
SESAQ
221
SKMLS
226
GVGGF
231
VLGLL
236
FLGAG
241
LFIYF
246
KNQKG
251
HSGLH
256
PTGLV
261
S
266
Mutation Information
DNA mutation:
None
Peptide Range:
236 ~ 260
Mut AA position:
248 (13 in Wild Type peptide)
Alignment
Wild Type:
"VLGLLFLGAGLFIYFKNQKGHSGLH
||||||||||||.||||||||||||
Mutant:
VLGLLFLGAGLFLYFKNQKGHSGLH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HLA-DRB5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay