Immunogenicity 8863
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SOCS6
Transcript ID
NM_199421
HLA INFO
C*05:01
TCR INFO
No TCR info found!
Full length protein sequence (440 aa)
MAENN
1
ENISK
6
NVDVR
11
PKTSR
16
SRSAD
21
RKDGY
26
VWSGK
31
KLSWS
36
KKSES
41
YSDAE
46
TVNGI
51
EKTEV
56
SLRNQ
61
ERKHS
66
CSSIE
71
LDLDH
76
SCGHR
81
FLGRS
86
LKQKL
91
QDAVG
96
QCFPI
101
KNCSS
106
RHSSG
111
LPSKR
116
KIHIS
121
ELMLD
126
KCPFP
131
PRSDL
136
AFRWH
141
FIKRH
146
TAPIN
151
SKSDE
156
WVSTD
161
LSQTE
166
LRDGQ
171
LKRRN
176
MEENI
181
NCFSH
186
TNVQP
191
CVITT
196
DNALC
201
REGPM
206
TGSVM
211
NLVSN
216
NSIED
221
SDMDS
226
DDEIL
231
TLCTS
236
SRKRN
241
KPKWD
246
LDDEI
251
LQLET
256
PPKYH
261
TQIDY
266
VHCLV
271
PDLLQ
276
INNNP
281
CYWGV
286
MDKYA
291
AEALL
296
EGKPE
301
GTFLL
306
RDSAQ
311
EDYLF
316
SVSFR
321
RYSRS
326
LHARI
331
EQWNH
336
NFSFD
341
AHDPC
346
VFHSP
351
DITGL
356
LEHYK
361
DPSAC
366
MFFEP
371
LLSTP
376
LIRTF
381
PFSLQ
386
HICRT
391
VICNC
396
TTYDG
401
IDALP
406
IPSSM
411
KLYLK
416
EYHYK
421
SKVRV
426
LRIDA
431
PEQQC
436
Mutation Information
DNA mutation:
None
Peptide Range:
73 ~ 103
Mut AA position:
85 (13 in Wild Type peptide)
Alignment
Wild Type:
"SIELDLDHSCGHRFLGRSLKQKLQD------
||||||||||||.|||||.||||||
Mutant:
SIELDLDHSCGHGFLGRSVKQKLQDAVGQCF"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SOCS4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay