Immunogenicity 8866

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DPYSL4
Transcript ID
NM_006426
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (572 aa)
MSFQG
1
KKSIP
6
RITSD
11
RLLIR
16
GGRIV
21
NDDQS
26
FYADV
31
HVEDG
36
LIKQI
41
GENLI
46
VPGGI
51
KTIDA
56
HGLMV
61
LPGGV
66
DVHTR
71
LQMPV
76
LGMTP
81
ADDFC
86
QGTKA
91
ALAGG
96
TTMIL
101
DHVFP
106
DTGVS
111
LLAAY
116
EQWRE
121
RADSA
126
ACCDY
131
SLHVD
136
ITRWH
141
ESIKE
146
ELEAL
151
VKEKG
156
VNSFL
161
VFMAY
166
KDRCQ
171
CSDSQ
176
MYEIF
181
SIIRD
186
LGALA
191
QVHAE
196
NGDIV
201
EEEQK
206
RLLEL
211
GITGP
216
EGHVL
221
SHPEE
226
VEAEA
231
VYRAV
236
TIAKQ
241
ANCPL
246
YVTKV
251
MSKGA
256
ADAIA
261
QAKRR
266
GVVVF
271
GEPIT
276
ASLGT
281
DGSHY
286
WSKNW
291
AKAAA
296
FVTSP
301
PVNPD
306
PTTAD
311
HLTCL
316
LSSGD
321
LQVTG
326
SAHCT
331
FTTAQ
336
KAVGK
341
DNFAL
346
IPEGT
351
NGIEE
356
RMSMV
361
WEKCV
366
ASGKM
371
DENEF
376
VAVTS
381
TNAAK
386
IFNFY
391
PRKGR
396
VAVGS
401
DADLV
406
IWNPK
411
ATKII
416
SAKTH
421
NLNVE
426
YNIFE
431
GVECR
436
GAPAV
441
VISQG
446
RVALE
451
DGKMF
456
VTPGA
461
GRFVP
466
RKTFP
471
DFVYK
476
RIKAR
481
NRLAE
486
IHGVP
491
RGLYD
496
GPVHE
501
VMVPA
506
KPGSG
511
APARA
516
SCPGK
521
ISVPP
526
VRNLH
531
QSGFS
536
LSGSQ
541
ADDHI
546
ARRTA
551
QKIMA
556
PPGGR
561
SNITS
566
LS
571
Mutation Information
DNA mutation:
None
Peptide Range:
4 ~ 28
Mut AA position:
16 (13 in Wild Type peptide)
Alignment
Wild Type:
"QGKKSIPRITSDRLLIRGGRIVNDD
||||||||||||.||||||||||||
Mutant:
QGKKSIPRITSDHLLIRGGRIVNDD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DPYSL4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay