Immunogenicity 8882

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
RUFY1
Transcript ID
NM_025158
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (708 aa)
MADRE
1
GGCAA
6
GRGRE
11
LEPEL
16
EPGPG
21
PGSAL
26
EPGEE
31
FEIVD
36
RSQLP
41
GPGDL
46
RSATR
51
PRAAE
56
GWSAP
61
ILTLA
66
RRATG
71
NLSAS
76
CGSAL
81
RAAAG
86
LGGGD
91
SGDGT
96
ARAAS
101
KCQMM
106
EERAN
111
LMHMM
116
KLSIK
121
VLLQS
126
ALSLG
131
RSLDA
136
DHAPL
141
QQFFV
146
VMEHC
151
LKHGL
156
KVKKS
161
FIGQN
166
KSFFG
171
PLELV
176
EKLCP
181
EASDI
186
ATSVR
191
NLPEL
196
KTAVG
201
RGRAW
206
LYLAL
211
MQKKL
216
ADYLK
221
VLIDN
226
KHLLS
231
EFYEP
236
EALMM
241
EEEGM
246
VIVGL
251
LVGLN
256
VLDAN
261
LCLKG
266
EDLDS
271
QVGVI
276
DFSLY
281
LKDVQ
286
DLDGG
291
KEHER
296
ITDVL
301
DQKNY
306
VEELN
311
RHLSC
316
TVGDL
321
QTKID
326
GLEKT
331
NSKLQ
336
EELSA
341
ATDRI
346
CSLQE
351
EQQQL
356
REQNE
361
LIRER
366
SEKSV
371
EITKQ
376
DTKVE
381
LETYK
386
QTRQG
391
LDEMY
396
SDVWK
401
QLKEE
406
KKVRL
411
ELEKE
416
LELQI
421
GMKTE
426
MEIAM
431
KLLEK
436
DTHEK
441
QDTLV
446
ALRQQ
451
LEEVK
456
AINLQ
461
MFHKA
466
QNAES
471
SLQQK
476
NEAIT
481
SFEGK
486
TNQVM
491
SSMKQ
496
MEERL
501
QHSER
506
ARQGA
511
EERSH
516
KLQQE
521
LGGRI
526
GALQL
531
QLSQL
536
HEQCS
541
SLEKE
546
LKSEK
551
EQRQA
556
LQREL
561
QHEKD
566
TSSLL
571
RMELQ
576
QVEGL
581
KKELR
586
ELQDE
591
KAELQ
596
KICEE
601
QEQAL
606
QEMGL
611
HLSQS
616
KLKME
621
DIKEV
626
NQALK
631
GHAWL
636
KDDEA
641
THCRQ
646
CEKEF
651
SISRR
656
KHHCR
661
NCGHI
666
FCNTC
671
SSNEL
676
ALPSY
681
PKPVR
686
VCDSC
691
HTLLL
696
QRCSS
701
TAS
706
Mutation Information
DNA mutation:
None
Peptide Range:
60 ~ 84
Mut AA position:
72 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGWSAPILTLARRATGNLSASCGSA
||||||||||||.||||||||||||
Mutant:
EGWSAPILTLARKATGNLSASCGSA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RUFY1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay