Immunogenicity 8889

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TBCK
Transcript ID
NM_001163437
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (854 aa)
MFPLK
1
DAEMG
6
AFTFF
11
ASALP
16
HDVCG
21
SNGLP
26
LTPNS
31
IKILG
36
RFQIL
41
KTITH
46
PRLCQ
51
YVDIS
56
RGKHE
61
RLVVV
66
AEHCE
71
RSLED
76
LLRER
81
KPVSC
86
STVLC
91
IAFEV
96
LQGLQ
101
YMNKH
106
GIVHR
111
ALSPH
116
NILLD
121
RKGHI
126
KLAKF
131
GLYHM
136
TAHGD
141
DVDFP
146
IGYPS
151
YLAPE
156
GRKLF
161
QSLDI
166
SERLK
171
FLLTL
176
DCVDD
181
TLIVL
186
AEEHG
191
CLDII
196
KELPE
201
TVIDL
206
LNKCL
211
TFHPS
216
KRPTP
221
DELMK
226
DKVFS
231
EVSPL
236
YTPFT
241
KPASL
246
FSSSL
251
RCADL
256
TLPED
261
ISQLC
266
KDINN
271
DYLAE
276
RSIEE
281
VYYLW
286
CLAGG
291
DLEKE
296
LVNKE
301
IIRSK
306
PPICT
311
LPNFL
316
FEDGE
321
SFGQG
326
RDRSS
331
LLDDT
336
TVTLS
341
LCQLR
346
NRLKD
351
VGGEA
356
FYPLL
361
EDDQS
366
NLPHS
371
NSNNE
376
LSAAA
381
TLPLI
386
IREKD
391
TEYQL
396
NRIIL
401
FDRLL
406
KAYPY
411
KKNQI
416
WKEAR
421
VDIPP
426
LMRGL
431
TWAAL
436
LGVEG
441
AIHAK
446
YDAID
451
KDTPI
456
PTDRQ
461
IEVDI
466
PRCHQ
471
YDELL
476
SSPEG
481
HAKFR
486
RVLKA
491
WVVSH
496
PDLVY
501
WQGLD
506
SLCAP
511
FLYLN
516
FNNEA
521
LAYAC
526
MSAFI
531
PKYLY
536
NFFLK
541
DNSHV
546
IQEYL
551
TVFSQ
556
MIAFH
561
DPELS
566
NHLNE
571
IGFIP
576
DLYAI
581
PWFLT
586
MFTHV
591
FPLHK
596
IFHLW
601
DTLLL
606
GNSSF
611
PFCIG
616
VAILQ
621
QLRDR
626
LLANG
631
FNECI
636
LLFSD
641
LPEID
646
IERCV
651
RESIN
656
LFCWT
661
PKSAT
666
YRQHA
671
QPPKP
676
SSDSS
681
GGRSS
686
APYFS
691
AECPD
696
PPKTD
701
LSRES
706
IPLND
711
LKSEV
716
SPRIS
721
AEDLI
726
DLCEL
731
TVTGH
736
FKTPS
741
KKTKS
746
SKPKL
751
LVVDI
756
RNSED
761
FIRGH
766
ISGSI
771
NIPFS
776
AAFTA
781
EGELT
786
QGPYT
791
AMLQN
796
FKGKV
801
IVIVG
806
HVAKH
811
TAEFA
816
AHLVK
821
MKYPR
826
ICILD
831
GGINK
836
IKPTG
841
LLTIP
846
SPQI
851
Mutation Information
DNA mutation:
None
Peptide Range:
406 ~ 430
Mut AA position:
418 (13 in Wild Type peptide)
Alignment
Wild Type:
"FDRLLKAYPYKKNQIWKEARVDIPP
||||||||||||.||||||||||||
Mutant:
FDRLLKAYPYKKKQIWKEARVDIPP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TBCK

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay