Immunogenicity 8905
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MARS2
Transcript ID
NM_138395
HLA INFO
C*07:02
TCR INFO
No TCR info found!
Full length protein sequence (593 aa)
MLRTS
1
VLRLL
6
GRTGA
11
SRLSL
16
LEDFG
21
PRYYS
26
SGSLS
31
AGDDA
36
CDVRA
41
YFTTP
46
IFYVN
51
AAPHI
56
GHLYS
61
ALLAD
66
ALCRH
71
RRLRG
76
PSTAA
81
TRFST
86
GTDEH
91
GLKIQ
96
QAAAT
101
AGLAP
106
TELCD
111
RVSEQ
116
FQQLF
121
QEAGI
126
SCTDF
131
IRTTE
136
ARHRV
141
AVQHF
146
WGVLK
151
SRGLL
156
YKGVY
161
EGWYC
166
ASDEC
171
FLPEA
176
KVTQQ
181
PGPSG
186
DSFPV
191
SLESG
196
HPVSW
201
TKEEN
206
YIFRL
211
SQFRK
216
PLQRW
221
LRGNP
226
QAITP
231
EPFHH
236
VVLQW
241
LDEEL
246
PDLSV
251
SRRSS
256
HLHWG
261
IPVPG
266
DDSQT
271
IYVWL
276
DALVN
281
YLTVI
286
GYPNA
291
EFKSW
296
WPATS
301
HIIGK
306
DILKF
311
HAIYW
316
PAFLL
321
GAGMS
326
PPQRI
331
CVHSH
336
WTVCG
341
QKMSK
346
SLGNV
351
VDPRT
356
CLNRY
361
TVDGF
366
RYFLL
371
RQGVP
376
NWDCD
381
YYDEK
386
VVKLL
391
NSELA
396
DALGG
401
LLNRC
406
TAKRI
411
NPSET
416
YPAFC
421
TTCFP
426
SEPGL
431
VGPSV
436
RAQAE
441
DYALV
446
SAVAT
451
LPKQV
456
ADHYD
461
NFRIY
466
KALEA
471
VSSCV
476
RQTNG
481
FVQRH
486
APWKL
491
NWESP
496
VDAPW
501
LGTVL
506
HVALE
511
CLRVF
516
GTLLQ
521
PVTPS
526
LADKL
531
LSRLG
536
VSASE
541
RSLGE
546
LYFLP
551
RFYGH
556
PCPFE
561
GRRLG
566
PETGL
571
LFPRL
576
DQSRT
581
WLVKA
586
HRT
591
Mutation Information
DNA mutation:
None
Peptide Range:
466 ~ 490
Mut AA position:
478 (13 in Wild Type peptide)
Alignment
Wild Type:
"NFRIYKALEAVSSCVRQTNGFVQRH
||||||||||||.||||||||||||
Mutant:
NFRIYKALEAVSRCVRQTNGFVQRH"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) MARS2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay