Immunogenicity 8915

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MRGPRF
Transcript ID
NM_145015
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (343 aa)
MAGNC
1
SWEAH
6
PGNRN
11
KMCPG
16
LSEAP
21
ELYSR
26
GFLTI
31
EQIAM
36
LPPPA
41
VMNYI
46
FLLLC
51
LCGLV
56
GNGLV
61
LWFFG
66
FSIKR
71
NPFSI
76
YFLHL
81
ASADV
86
GYLFS
91
KAVFS
96
ILNTG
101
GFLGT
106
FADYI
111
RSVCR
116
VLGLC
121
MFLTG
126
VSLLP
131
AVSAE
136
RCASV
141
IFPAW
146
YWRRR
151
PKRLS
156
AVVCA
161
LLWVL
166
SLLVT
171
CLHNY
176
FCVFL
181
GRGAP
186
GAACR
191
HMDIF
196
LGILL
201
FLLCC
206
PLMVL
211
PCLAL
216
ILHVE
221
CRARR
226
RQRSA
231
KLNHV
236
ILAMV
241
SVFLV
246
SSIYL
251
GIDWF
256
LFWVF
261
QIPAP
266
FPEYV
271
TDLCI
276
CINSS
281
AKPIV
286
YFLAG
291
RDKSQ
296
RLWEP
301
LRVVF
306
QRALR
311
DGAEL
316
GEAGG
321
STPNT
326
VTMEM
331
QCPPG
336
NAS
341
Mutation Information
DNA mutation:
None
Peptide Range:
34 ~ 58
Mut AA position:
46 (13 in Wild Type peptide)
Alignment
Wild Type:
"TIEQIAMLPPPAVMNYIFLLLCLCG
||||||||||||.||||||||||||
Mutant:
TIEQIAMLPPPAIMNYIFLLLCLCG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MRGPRF

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay