Immunogenicity 8936

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRSS27
Transcript ID
NM_031948
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (290 aa)
MRRPA
1
AVPLL
6
LLLCF
11
GSQRA
16
KAATA
21
CGRPR
26
MLNRM
31
VGGQD
36
TQEGE
41
WPWQV
46
SIQRN
51
GSHFC
56
GGSLI
61
AEQWV
66
LTAAH
71
CFRNT
76
SETSL
81
YQVLL
86
GARQL
91
VQPGP
96
HAMYA
101
RVRQV
106
ESNPL
111
YQGTA
116
SSADV
121
ALVEL
126
EAPVP
131
FTNYI
136
LPVCL
141
PDPSV
146
IFETG
151
MNCWV
156
TGWGS
161
PSEED
166
LLPEP
171
RILQK
176
LAVPI
181
IDTPK
186
CNLLY
191
SKDTE
196
FGYQP
201
KTIKN
206
DMLCA
211
GFEEG
216
KKDAC
221
KGDSG
226
GPLVC
231
LVGQS
236
WLQAG
241
VISWG
246
EGCAR
251
QNRPG
256
VYIRV
261
TAHHN
266
WIHRI
271
IPKLQ
276
FQPAR
281
LGGQK
286
Mutation Information
DNA mutation:
None
Peptide Range:
234 ~ 258
Mut AA position:
246 (13 in Wild Type peptide)
Alignment
Wild Type:
"VCLVGQSWLQAGVISWGEGCARQNR
||||||||||||.||||||||||||
Mutant:
VCLVGQSWLQAGGISWGEGCARQNR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRSS27

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay