Immunogenicity 8942

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
NRXN3
Transcript ID
NM_138970
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (432 aa)
MHLRI
1
HARRS
6
PPRRP
11
AWTLG
16
IWFLF
21
WGCIV
26
SSVWS
31
SSNVA
36
SSSST
41
SSSPG
46
SHSQH
51
EHHFH
56
GSKHH
61
SVPIS
66
IYRSP
71
VSLRG
76
GHAGA
81
TYIFG
86
KSGGL
91
ILYTW
96
PANDR
101
PSTRS
106
DRLAV
111
GFSTT
116
VKDGI
121
LVRID
126
SAPGL
131
GDFLQ
136
LHIEQ
141
GKIGV
146
VFNIG
151
TVDIS
156
IKEER
161
TPVND
166
GKYHV
171
VRFTR
176
NGGNA
181
TLQVD
186
NWPVN
191
EHYPT
196
GRQLT
201
IFNTQ
206
AQIAI
211
GGKDK
216
GRLFQ
221
GQLSG
226
LYYDG
231
LKVLN
236
MAAEN
241
NPNIK
246
INGSV
251
RLVGE
256
VPSIL
261
GTTQT
266
TSMPP
271
EMSTT
276
VMETT
281
TTMAT
286
TTTRK
291
NRSTA
296
SIQPT
301
SDDLV
306
SSAEC
311
SSDDE
316
DFVEC
321
EPSTG
326
RSANP
331
TEPGI
336
RRVPG
341
ASEVI
346
RESSS
351
TTGMV
356
VGIVA
361
AAALC
366
ILILL
371
YAMYK
376
YRNRD
381
EGSYQ
386
VDETR
391
NYISN
396
SAQSN
401
GTLMK
406
EKQQS
411
SKSGH
416
KKQKN
421
KDREY
426
YV
431
Mutation Information
DNA mutation:
None
Peptide Range:
330 ~ 354
Mut AA position:
342 (13 in Wild Type peptide)
Alignment
Wild Type:
"GRSANPTEPGIRRVPGASEVIRESS
||||||||||||.||||||||||||
Mutant:
GRSANPTEPGIRQVPGASEVIRESS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NRXN3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay