Immunogenicity 8950

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
WFIKKN2
Transcript ID
NM_175575
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (576 aa)
MWAPR
1
CRRFW
6
SRWEQ
11
VAALL
16
LLLLL
21
LGVPP
26
RSLAL
31
PPIRY
36
SHAGI
41
CPNDM
46
NPNLW
51
VDAQS
56
TCRRE
61
CETDQ
66
ECETY
71
EKCCP
76
NVCGT
81
KSCVA
86
ARYMD
91
VKGKK
96
GPVGM
101
PKEAT
106
CDHFM
111
CLQQG
116
SECDI
121
WDGQP
126
VCKCK
131
DRCEK
136
EPSFT
141
CASDG
146
LTYYN
151
RCYMD
156
AEACS
161
KGITL
166
AVVTC
171
RYHFT
176
WPNTS
181
PPPPE
186
TTMHP
191
TTASP
196
ETPEL
201
DMAAP
206
ALLNN
211
PVHQS
216
VTMGE
221
TVSFL
226
CDVVG
231
RPRPE
236
ITWEK
241
QLEDR
246
ENVVM
251
RPNHV
256
RGNVV
261
VTNIA
266
QLVIY
271
NAQLQ
276
DAGIY
281
TCTAR
286
NVAGV
291
LRADF
296
PLSVV
301
RGHQA
306
AATSE
311
SSPNG
316
TAFPA
321
AECLK
326
PPDSE
331
DCGEE
336
QTRWH
341
FDAQA
346
NNCLT
351
FTFGH
356
CHRNL
361
NHFET
366
YEACM
371
LACMS
376
GPLAA
381
CSLPA
386
LQGPC
391
KAYAP
396
RWAYN
401
SQTGQ
406
CQSFV
411
YGGCE
416
GNGNN
421
FESRE
426
ACEES
431
CPFPR
436
GNQRC
441
RACKP
446
RQKLV
451
TSFCR
456
SDFVI
461
LGRVS
466
ELTEE
471
PDSGR
476
ALVTV
481
DEVLK
486
DEKMG
491
LKFLG
496
QEPLE
501
VTLLH
506
VDWAC
511
PCPNV
516
TVSEM
521
PLIIM
526
GEVDG
531
GMAML
536
RPDSF
541
VGASS
546
ARRVR
551
KLREV
556
MHKKT
561
CDVLK
566
EFLGL
571
H
576
Mutation Information
DNA mutation:
None
Peptide Range:
249 ~ 273
Mut AA position:
261 (13 in Wild Type peptide)
Alignment
Wild Type:
"DRENVVMRPNHVRGNVVVTNIAQLV
||||||||||||.||||||||||||
Mutant:
DRENVVMRPNHVCGNVVVTNIAQLV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) WFIKKN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay