Immunogenicity 8956
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCDH15
Transcript ID
NM_001142763
HLA INFO
B*07:02
TCR INFO
No TCR info found!
Full length protein sequence (1962 aa)
MFRQF
1
YLWTC
6
LASGI
11
ILGSL
16
FEICL
21
GQYDD
26
DWQYE
31
DCKLA
36
RGGPP
41
ATIVA
46
IDEES
51
RNGTI
56
LVDNM
61
LIKGT
66
AGGPD
71
PTIEL
76
SLKDN
81
VDYWV
86
LMDPV
91
KQMLF
96
LNSTG
101
RVLDR
106
DPPMN
111
IHSIV
116
VQVQC
121
INKKV
126
GTIIY
131
HEVRI
136
VVRDR
141
NDNSP
146
TFKHE
151
SYYAT
156
VNELT
161
PVGTT
166
IFTGF
171
SGDNG
176
ATDID
181
DGPNG
186
QIEYV
191
IQYNP
196
DDPTS
201
NDTFE
206
IPLML
211
TGNIV
216
LRKRL
221
NYEDK
226
TRYFV
231
IIQAN
236
DRAQN
241
LNERR
246
TTTTT
251
LTVDV
256
LDGDD
261
LGPMF
266
LPCVL
271
VPNTR
276
DCRPL
281
TYQAA
286
IPELR
291
TPEEL
296
NPIIV
301
TPPIQ
306
AIDQD
311
RNIQP
316
PSDRP
321
GILYS
326
ILVGT
331
PEDYP
336
RFFHM
341
HPRTA
346
ELSLL
351
EPVNR
356
DFHQK
361
FDLVI
366
KAEQD
371
NGHPL
376
PAFAG
381
LHIEI
386
LDENN
391
QSPYF
396
TMPSY
401
QGYIL
406
ESAPV
411
GATIS
416
DSLNL
421
TSPLR
426
IVALD
431
KDIED
436
TKDPE
441
LHLFL
446
NDYTS
451
VFTVT
456
QTGIT
461
RYLTL
466
LQPVD
471
REEQQ
476
TYTFS
481
ITAFD
486
GVQES
491
EPVIV
496
NIQVM
501
DANDN
506
TPTFP
511
EISYD
516
VYVYT
521
DMRPG
526
DSVIQ
531
LTAVD
536
ADEGS
541
NGEIT
546
YEILV
551
GAQGD
556
FIINK
561
TTGLI
566
TIAPG
571
VEMIV
576
GRTYA
581
LTVQA
586
ADNAP
591
PAERR
596
NSICT
601
VYIEV
606
LPPNN
611
QSPPR
616
FPQLM
621
YSLEI
626
SEAMR
631
VGAVL
636
LNLQA
641
TDREG
646
DSITY
651
AIENG
656
DPQRV
661
FNLSE
666
TTGIL
671
TLGKA
676
LDRES
681
TDRYI
686
LIITA
691
SDGRP
696
DGTST
701
ATVNI
706
VVTDV
711
NDNAP
716
VFDPY
721
LPRNL
726
SVVEE
731
EANAF
736
VGQVK
741
ATDPD
746
AGING
751
QVHYS
756
LGNFN
761
NLFRI
766
TSNGS
771
IYTAV
776
KLNRE
781
VRDYY
786
ELVVV
791
ATDGA
796
VHPRH
801
STLTL
806
AIKVL
811
DIDDN
816
SPVFT
821
NSTYT
826
VLVEE
831
NLPAG
836
TTILQ
841
IEAKD
846
VDLGA
851
NVSYR
856
IRSPE
861
VKHFF
866
ALHPF
871
TGELS
876
LLRSL
881
DYEAF
886
PDQEA
891
SITFL
896
VEAFD
901
IYGTM
906
PPGIA
911
TVTVI
916
VKDMN
921
DYPPV
926
FSKRI
931
YKGMV
936
APDAV
941
KGTPI
946
TTVYA
951
EDADP
956
PGLPA
961
SRVRY
966
RVDDV
971
QFPYP
976
ASIFE
981
VEEDS
986
GRVIT
991
RVNLN
996
EEPTT
1001
IFKLV
1006
VVAFD
1011
DGEPV
1016
MSSSA
1021
TVKIL
1026
VLHPG
1031
EIPRF
1036
TQEEY
1041
RPPPV
1046
SELAT
1051
KGTMV
1056
GVISA
1061
AAINQ
1066
SIVYS
1071
IVSGN
1076
EEDTF
1081
GINNI
1086
TGVIY
1091
VNGPL
1096
DYETR
1101
TSYVL
1106
RVQAD
1111
SLEVV
1116
LANLR
1121
VPSKS
1126
NTAKV
1131
YIEIQ
1136
DENNH
1141
PPVFQ
1146
KKFYI
1151
GGVSE
1156
DARMF
1161
TSVLR
1166
VKATD
1171
KDTGN
1176
YSVMA
1181
YRLII
1186
PPIKE
1191
GKEGF
1196
VVETY
1201
TGLIK
1206
TAMLF
1211
HNMRR
1216
SYFKF
1221
QVIAT
1226
DDYGK
1231
GLSGK
1236
ADVLV
1241
SVVNQ
1246
LDMQV
1251
IVSNV
1256
PPTLV
1261
EKKIE
1266
DLTEI
1271
LDRYV
1276
QEQIP
1281
GAKVV
1286
VESIG
1291
ARRHG
1296
DAFSL
1301
EDYTK
1306
CDLTV
1311
YAIDP
1316
QTNRA
1321
IDRNE
1326
LFKFL
1331
DGKLL
1336
DINKD
1341
FQPYY
1346
GEGGR
1351
ILEIR
1356
TPEAV
1361
TSIKK
1366
RGESL
1371
GYTEG
1376
ALLAL
1381
AFIII
1386
LCCIP
1391
AILVV
1396
LVSYR
1401
QFKVR
1406
QAECT
1411
KTARI
1416
QAALP
1421
AAKPA
1426
VPAPA
1431
PVAAP
1436
PPPPP
1441
PPPGA
1446
HLYEE
1451
LGDSS
1456
MHNLF
1461
LLYHF
1466
QQSRG
1471
NNSVS
1476
EDRKH
1481
QQVVM
1486
PFSSN
1491
TIEAH
1496
KSAHV
1501
DGSLK
1506
SNKLK
1511
SARKF
1516
TFLSD
1521
EDDLS
1526
AHNPL
1531
YKENI
1536
SQVST
1541
NSDIS
1546
QRTDF
1551
VDPFS
1556
PKIQA
1561
KSKSL
1566
RGPRE
1571
KIQRL
1576
WSQSV
1581
SLPRR
1586
LMRKV
1591
PNRPE
1596
IIDLQ
1601
QWQGT
1606
RQKAE
1611
NENTG
1616
ICTNK
1621
RGSSN
1626
PLLTT
1631
EEANL
1636
TEKEE
1641
IRQGE
1646
TLMIE
1651
GTEQL
1656
KSLSS
1661
DSSFC
1666
FPRPH
1671
FSFST
1676
LPTVS
1681
RTVEL
1686
KSEPN
1691
VISSP
1696
AECSL
1701
ELSPS
1706
RPCVL
1711
HSSLS
1716
RRETP
1721
ICMLP
1726
IETER
1731
NIFEN
1736
FAHPP
1741
NISPS
1746
ACPLP
1751
PPPPI
1756
SPPSP
1761
PPAPA
1766
PLAPP
1771
PDISP
1776
FSLFC
1781
PPPSP
1786
PSIPL
1791
PLPPP
1796
TFFPL
1801
SVSTS
1806
GPPTP
1811
PLLPP
1816
FPTPL
1821
PPPPP
1826
SIPCP
1831
PPPSA
1836
SFLST
1841
ECVCI
1846
TGVKC
1851
TTNLM
1856
PAEKI
1861
KSSMT
1866
QLSTT
1871
TVCKT
1876
DPQRE
1881
PKGIL
1886
RHVKN
1891
LAELE
1896
KSVAN
1901
MYSQI
1906
EKNYL
1911
RTNVS
1916
ELQTM
1921
CPSEV
1926
TNMEI
1931
TSEQN
1936
KGSLN
1941
NIVEG
1946
TEKQS
1951
HSQST
1956
SL
1961
Mutation Information
DNA mutation:
None
Peptide Range:
950 ~ 974
Mut AA position:
962 (13 in Wild Type peptide)
Alignment
Wild Type:
"ITTVYAEDADPPGLPASRVRYRVDD
||||||||||||.||||||||||||
Mutant:
ITTVYAEDADPPVLPASRVRYRVDD"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PCDH15
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay