Immunogenicity 8979
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GPR158
Transcript ID
NM_020752
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (1215 aa)
MGAMA
1
YPLLL
6
CLLLA
11
QLGLG
16
AVGAS
21
RDPQG
26
RPDSP
31
RERTP
36
KGKPH
41
AQQPG
46
RASAS
51
DSSAP
56
WSRST
61
DGTIL
66
AQKLA
71
EEVPM
76
DVASY
81
LYTGD
86
SHQLK
91
RANCS
96
GRYEL
101
AGLPG
106
KWPAL
111
ASAHP
116
SLHRA
121
LDTLT
126
HATNF
131
LNVML
136
QSNKS
141
REQNL
146
QDDLD
151
WYQAL
156
VWSLL
161
EGEPS
166
ISRAA
171
ITFST
176
DSLSA
181
PAPQV
186
FLQAT
191
REESR
196
ILLQD
201
LSSSA
206
PHLAN
211
ATLET
216
EWFHG
221
LRRKW
226
RPHLH
231
RRGPN
236
QGPRG
241
LGHSW
246
RRKDG
251
LGGDK
256
SHFKW
261
SPPYL
266
ECENG
271
SYKPG
276
WLVTL
281
SSAIY
286
GLQPN
291
LVPEF
296
RGVMK
301
VDINL
306
QKVDI
311
DQCSS
316
DGWFS
321
GTHKC
326
HLNNS
331
ECMPI
336
KGLGF
341
VLGAY
346
ECICK
351
AGFYH
356
PGVLP
361
VNNFR
366
RRGPD
371
QHISG
376
STKDV
381
SEEAY
386
VCLPC
391
REGCP
396
FCADD
401
SPCFV
406
QEDKY
411
LRLAI
416
ISFQA
421
LCMLL
426
DFVSM
431
LVVYH
436
FRKAK
441
SIRAS
446
GLILL
451
ETILF
456
GSLLL
461
YFPVV
466
ILYFE
471
PSTFR
476
CILLR
481
WARLL
486
GFATV
491
YGTVT
496
LKLHR
501
VLKVF
506
LSRTA
511
QRIPY
516
MTGGR
521
VMRML
526
AVILL
531
VVFWF
536
LIGWT
541
SSVCQ
546
NLEKQ
551
ISLIG
556
QGKTS
561
DHLIF
566
NMCLI
571
DRWDY
576
MTAVA
581
EFLFL
586
LWGVY
591
LCYAV
596
RTVPS
601
AFHEP
606
RYMAV
611
AVHNE
616
LIISA
621
IFHTI
626
RFVLA
631
SRLQS
636
DWMLM
641
LYFAH
646
THLTV
651
TVTIG
656
LLLIP
661
KFSHS
666
SNNPR
671
DDIAT
676
EAYED
681
ELDMG
686
RSGSY
691
LNSSI
696
NSAWS
701
EHSLD
706
PEDIR
711
DELKK
716
LYAQL
721
EIYKR
726
KKMIT
731
NNPHL
736
QKKRC
741
SKKGL
746
GRSIM
751
RRITE
756
IPETV
761
SRQCS
766
KEDKE
771
GADHG
776
TAKGT
781
ALIRK
786
NPPES
791
SGNTG
796
KSKEE
801
TLKNR
806
VFSLK
811
KSHST
816
YDHVR
821
DQTEE
826
SSSLP
831
TESQE
836
EETTE
841
NSTLE
846
SLSGK
851
KLTQK
856
LKEDS
861
EAEST
866
ESVPL
871
VCKSA
876
SAHNL
881
SSEKK
886
TGHPR
891
TSMLQ
896
KSLSV
901
IASAK
906
EKTLG
911
LAGKT
916
QTAGV
921
EERTK
926
SQKPL
931
PKDKE
936
TNRNH
941
SNSDN
946
TETKD
951
PAPQN
956
SNPAE
961
EPRKP
966
QKSGI
971
MKQQR
976
VNPTT
981
ANSDL
986
NPGTT
991
QMKDN
996
FDIGE
1001
VCPWE
1006
VYDLT
1011
PGPVP
1016
SESKV
1021
QKHVS
1026
IVASE
1031
MEKNP
1036
TFSLK
1041
EKSHH
1046
KPKAA
1051
EVCQQ
1056
SNQKR
1061
IDKAE
1066
VCLWE
1071
SQGQS
1076
ILEDE
1081
KLLIS
1086
KTPVL
1091
PERAK
1096
EENGG
1101
QPRAA
1106
NVCAG
1111
QSEEL
1116
PPKAV
1121
ASKTE
1126
NENLN
1131
QIGHQ
1136
EKKTS
1141
SSEEN
1146
VRGSY
1151
NSSNN
1156
FQQPL
1161
TSRAE
1166
VCPWE
1171
FETPA
1176
QPNAG
1181
RSVAL
1186
PASSA
1191
LSANK
1196
IAGPR
1201
KEEIW
1206
DSFKV
1211
Mutation Information
DNA mutation:
None
Peptide Range:
311 ~ 335
Mut AA position:
323 (13 in Wild Type peptide)
Alignment
Wild Type:
"QKVDIDQCSSDGWFSGTHKCHLNNS
||||||||||||.||||||||||||
Mutant:
QKVDIDQCSSDGCFSGTHKCHLNNS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) GPR158
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay