Immunogenicity 8997
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
E2F1
Transcript ID
NM_002900
HLA INFO
C*03:04
TCR INFO
No TCR info found!
Full length protein sequence (1247 aa)
MMREW
1
VLLMS
6
VLLCG
11
LAGPT
16
HLFQP
21
SLVLD
26
MAKVL
31
LDNYC
36
FPENL
41
LGMQE
46
AIQQA
51
IKSHE
56
ILSIS
61
DPQTL
66
ASVLT
71
AGVQS
76
SLNDP
81
RLVIS
86
YEPST
91
PEPPP
96
QVPAL
101
TSLSE
106
EELLA
111
WLQRG
116
LRHEV
121
LEGNV
126
GYLRV
131
DSVPG
136
QEVLS
141
MMGEF
146
LVAHV
151
WGNLM
156
GTSAL
161
VLDLR
166
HCTGG
171
QVSGI
176
PYIIS
181
YLHPG
186
NTILH
191
VDTIY
196
NRPSN
201
TTTEI
206
WTLPQ
211
VLGER
216
YGADK
221
DVVVL
226
TSSQT
231
RGVAE
236
DIAHI
241
LKQMR
246
RAIVV
251
GERTG
256
GGALD
261
LRKLR
266
IGESD
271
FFFTV
276
PVSRS
281
LGPLG
286
GGSQT
291
WEGSG
296
VLPCV
301
GTPAE
306
QALEK
311
ALAIL
316
TLRSA
321
LPGVV
326
HCLQE
331
VLKDY
336
YTLVD
341
RVPTL
346
LQHLA
351
SMDFS
356
TVVSE
361
EDLVT
366
KLNAG
371
LQAAS
376
EDPRL
381
LVRAI
386
GPTET
391
PSWPA
396
PDAAA
401
EDSPG
406
VAPEL
411
PEDEA
416
IRQAL
421
VDSVF
426
QVSVL
431
PGNVG
436
YLRFD
441
SFADA
446
SVLGV
451
LAPYV
456
LRQVW
461
EPLQD
466
TEHLI
471
MDLRH
476
NPGGP
481
SSAVP
486
LLLSY
491
FQGPE
496
AGPVH
501
LFTTY
506
DRRTN
511
ITQEH
516
FSHME
521
LPGPR
526
YSTQR
531
GVYLL
536
TSHRT
541
ATAAE
546
EFAFL
551
MQSLG
556
WATLV
561
GEITA
566
GNLLH
571
TRTVP
576
LLDTP
581
EGSLA
586
LTVPV
591
LTFID
596
NHGEA
601
WLGGG
606
VVPDA
611
IVLAE
616
EALDK
621
AQEVL
626
EFHQS
631
LGALV
636
EGTGH
641
LLEAH
646
YARPE
651
VVGQT
656
SALLR
661
AKLAQ
666
GAYRT
671
AVDLE
676
SLASQ
681
LTADL
686
QEVSG
691
DHRLL
696
VFHSP
701
GELVV
706
EEAPP
711
PPPAV
716
PSPEE
721
LTYLI
726
EALFK
731
TEVLP
736
GQLGY
741
LRFDA
746
MAELE
751
TVKAV
756
GPQLV
761
RLVWQ
766
QLVDT
771
AALVI
776
DLRYN
781
PGSYS
786
TAIPL
791
LCSYF
796
FEAEP
801
RQHLY
806
SVFDR
811
ATSKV
816
TEVWT
821
LPQVA
826
GQRYG
831
SHKDL
836
YILMS
841
HTSGS
846
AAEAF
851
AHTMQ
856
DLQRA
861
TVIGE
866
PTAGG
871
ALSVG
876
IYQVG
881
SSPLY
886
ASMPT
891
QMAMS
896
ATTGK
901
AWDLA
906
GVEPD
911
ITVPM
916
SEALS
921
IAQDI
926
VALRA
931
KVPTV
936
LQTAG
941
KLVAD
946
NYASA
951
ELGAK
956
MATKL
961
SGLQS
966
RYSRV
971
TSEVA
976
LAEIL
981
GADLQ
986
MLSGD
991
PHLKA
996
AHIPE
1001
NAKDR
1006
IPGIV
1011
PMQIP
1016
SPEVF
1021
EELIK
1026
FSFHT
1031
NVLED
1036
NIGYL
1041
RFDMF
1046
GDGEL
1051
LTQVS
1056
RLLVE
1061
HIWKK
1066
IMHTD
1071
AMIID
1076
MRFNI
1081
GGPTS
1086
SIPIL
1091
CSYFF
1096
DEGPP
1101
VLLDK
1106
IYSRP
1111
DDSVS
1116
ELWTH
1121
AQVVG
1126
ERYGS
1131
KKSMV
1136
ILTSS
1141
VTAGT
1146
AEEFT
1151
YIMKR
1156
LGRAL
1161
VIGEV
1166
TSGGC
1171
QPPQT
1176
YHVDD
1181
TNLYL
1186
TIPTA
1191
RSVGA
1196
SDGSS
1201
WEGVG
1206
VTPHV
1211
VVPAE
1216
EALAR
1221
AKEML
1226
QHNQL
1231
RVKRS
1236
PGLQD
1241
HL
1246
Mutation Information
DNA mutation:
None
Peptide Range:
528 ~ 552
Mut AA position:
540 (13 in Wild Type peptide)
Alignment
Wild Type:
"GPRYSTQRGVYLLTSHRTATAAEEF
||||||||||||.||||||||||||
Mutant:
GPRYSTQRGVYLFTSHRTATAAEEF"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) RBP3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay