Immunogenicity 9007

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DLG2
Transcript ID
NM_001142699
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (975 aa)
MGIFK
1
SSLFQ
6
ALLDI
11
QEFYE
16
VTLLN
21
SQKSC
26
EQKIE
31
EANQV
36
LQKWE
41
KTSLL
46
APCHD
51
RLQKS
56
SELTD
61
CSGSK
66
ENASC
71
IEQNK
76
ENQSF
81
ENETD
86
ETTTQ
91
NQGRC
96
PAQNC
101
SVEAP
106
AWMPV
111
HHCTK
116
YRYQD
121
EDAPH
126
DHSLP
131
RLTHE
136
VRGPE
141
LVHVS
146
EKNLS
151
QIENV
156
HGYVL
161
QSHIS
166
PLKAS
171
PAPII
176
VNTDT
181
LDTIP
186
YVNGT
191
EIEYE
196
FEEIT
201
LERGN
206
SGLGF
211
SIAGG
216
TDNPH
221
IGDDP
226
GIFIT
231
KIIPG
236
GAAAE
241
DGRLR
246
VNDCI
251
LRVNE
256
VDVSE
261
VSHSK
266
AVEAL
271
KEAGS
276
IVRLY
281
VRRRR
286
PILET
291
VVEIK
296
LFKGP
301
KGLGF
306
SIAGG
311
VGNQH
316
IPGDN
321
SIYVT
326
KIIDG
331
GAAQK
336
DGRLQ
341
VGDRL
346
LMVNN
351
YSLEE
356
VTHEE
361
AVAIL
366
KNTSE
371
VVYLK
376
VGKPT
381
TIYMT
386
DPYGP
391
PDITH
396
SYSPP
401
MENHL
406
LSGNN
411
GTLEY
416
KTSLP
421
PISPG
426
RYSPI
431
PKHML
436
VDDDY
441
TRPPE
446
PVYST
451
VNKLC
456
DKPAS
461
PRHYS
466
PVECD
471
KSFLL
476
SAPYS
481
HYHLG
486
LLPDS
491
EMTSH
496
SQHST
501
ATRQP
506
SMTLQ
511
RAVSL
516
EGEPR
521
KVVLH
526
KGSTG
531
LGFNI
536
VGGED
541
GEGIF
546
VSFIL
551
AGGPA
556
DLSGE
561
LQRGD
566
QILSV
571
NGIDL
576
RGASH
581
EQAAA
586
ALKGA
591
GQTVT
596
IIAQY
601
QPEDY
606
ARFEA
611
KIHDL
616
REQMM
621
NHSMS
626
SGSGS
631
LRTNQ
636
KRSLY
641
VRAMF
646
DYDKS
651
KDSGL
656
PSQGL
661
SFKYG
666
DILHV
671
INASD
676
DEWWQ
681
ARRVM
686
LEGDS
691
EEMGV
696
IPSKR
701
RVERK
706
ERARL
711
KTVKF
716
NAKPG
721
VIDSK
726
GSFND
731
KRKKS
736
FIFSR
741
KFPFY
746
KNKEQ
751
SEQET
756
SDPER
761
GQEDL
766
ILSYE
771
PVTRQ
776
EINYT
781
RPVII
786
LGPMK
791
DRIND
796
DLISE
801
FPDKF
806
GSCVP
811
HTTRP
816
KRDYE
821
VDGRD
826
YHFVI
831
SREQM
836
EKDIQ
841
EHKFI
846
EAGQY
851
NDNLY
856
GTSVQ
861
SVRFV
866
AERGK
871
HCILD
876
VSGNA
881
IKRLQ
886
VAQLY
891
PIAIF
896
IKPRS
901
LEPLM
906
EMNKR
911
LTEEQ
916
AKKTY
921
DRAIK
926
LEQEF
931
GEYFT
936
AIVQG
941
DTLED
946
IYNQC
951
KLVIE
956
EQSGP
961
FIWIP
966
SKEKL
971
Mutation Information
DNA mutation:
None
Peptide Range:
52 ~ 76
Mut AA position:
64 (13 in Wild Type peptide)
Alignment
Wild Type:
"PCHDRLQKSSELTDCSGSKENASCI
||||||||||||.||||||||||||
Mutant:
PCHDRLQKSSELKDCSGSKENASCI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DLG2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay