Immunogenicity 9030
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DCC
Transcript ID
NM_005215
HLA INFO
C*05:01
TCR INFO
No TCR info found!
Full length protein sequence (1447 aa)
MENSL
1
RCVWV
6
PKLAF
11
VLFGA
16
SLFSA
21
HLQVT
26
GFQIK
31
AFTAL
36
RFLSE
41
PSDAV
46
TMRGG
51
NVLLD
56
CSAES
61
DRGVP
66
VIKWK
71
KDGIH
76
LALGM
81
DERKQ
86
QLSNG
91
SLLIQ
96
NILHS
101
RHHKP
106
DEGLY
111
QCEAS
116
LGDSG
121
SIISR
126
TAKVA
131
VAGPL
136
RFLSQ
141
TESVT
146
AFMGD
151
TVLLK
156
CEVIG
161
EPMPT
166
IHWQK
171
NQQDL
176
TPIPG
181
DSRVV
186
VLPSG
191
ALQIS
196
RLQPG
201
DIGIY
206
RCSAR
211
NPASS
216
RTGNE
221
AEVRI
226
LSDPG
231
LHRQL
236
YFLQR
241
PSNVV
246
AIEGK
251
DAVLE
256
CCVSG
261
YPPPS
266
FTWLR
271
GEEVI
276
QLRSK
281
KYSLL
286
GGSNL
291
LISNV
296
TDDDS
301
GMYTC
306
VVTYK
311
NENIS
316
ASAEL
321
TVLVP
326
PWFLN
331
HPSNL
336
YAYES
341
MDIEF
346
ECTVS
351
GKPVP
356
TVNWM
361
KNGDV
366
VIPSD
371
YFQIV
376
GGSNL
381
RILGV
386
VKSDE
391
GFYQC
396
VAENE
401
AGNAQ
406
TSAQL
411
IVPKP
416
AIPSS
421
SVLPS
426
APRDV
431
VPVLV
436
SSRFV
441
RLSWR
446
PPAEA
451
KGNIQ
456
TFTVF
461
FSREG
466
DNRER
471
ALNTT
476
QPGSL
481
QLTVG
486
NLKPE
491
AMYTF
496
RVVAY
501
NEWGP
506
GESSQ
511
PIKVA
516
TQPEL
521
QVPGP
526
VENLQ
531
AVSTS
536
PTSIL
541
ITWEP
546
PAYAN
551
GPVQG
556
YRLFC
561
TEVST
566
GKEQN
571
IEVDG
576
LSYKL
581
EGLKK
586
FTEYS
591
LRFLA
596
YNRYG
601
PGVST
606
DDITV
611
VTLSD
616
VPSAP
621
PQNVS
626
LEVVN
631
SRSIK
636
VSWLP
641
PPSGT
646
QNGFI
651
TGYKI
656
RHRKT
661
TRRGE
666
METLE
671
PNNLW
676
YLFTG
681
LEKGS
686
QYSFQ
691
VSAMT
696
VNGTG
701
PPSNW
706
YTAET
711
PENDL
716
DESQV
721
PDQPS
726
SLHVR
731
PQTNC
736
IIMSW
741
TPPLN
746
PNIVV
751
RGYII
756
GYGVG
761
SPYAE
766
TVRVD
771
SKQRY
776
YSIER
781
LESSS
786
HYVIS
791
LKAFN
796
NAGEG
801
VPLYE
806
SATTR
811
SITDP
816
TDPVD
821
YYPLL
826
DDFPT
831
SVPDL
836
STPML
841
PPVGV
846
QAVAL
851
THDAV
856
RVSWA
861
DNSVP
866
KNQKT
871
SEVRL
876
YTVRW
881
RTSFS
886
ASAKY
891
KSEDT
896
TSLSY
901
TATGL
906
KPNTM
911
YEFSV
916
MVTKN
921
RRSST
926
WSMTA
931
HATTY
936
EAAPT
941
SAPKD
946
LTVIT
951
REGKP
956
RAVIV
961
SWQPP
966
LEANG
971
KITAY
976
ILFYT
981
LDKNI
986
PIDDW
991
IMETI
996
SGDRL
1001
THQIM
1006
DLNLD
1011
TMYYF
1016
RIQAR
1021
NSKGV
1026
GPLSD
1031
PILFR
1036
TLKVE
1041
HPDKM
1046
ANDQG
1051
RHGDG
1056
GYWPV
1061
DTNLI
1066
DRSTL
1071
NEPPI
1076
GQMHP
1081
PHGSV
1086
TPQKN
1091
SNLLV
1096
IIVVT
1101
VGVIT
1106
VLVVV
1111
IVAVI
1116
CTRRS
1121
SAQQR
1126
KKRAT
1131
HSAGK
1136
RKGSQ
1141
KDLRP
1146
PDLWI
1151
HHEEM
1156
EMKNI
1161
EKPSG
1166
TDPAG
1171
RDSPI
1176
QSCQD
1181
LTPVS
1186
HSQSE
1191
TQLGS
1196
KSTSH
1201
SGQDT
1206
EEAGS
1211
SMSTL
1216
ERSLA
1221
ARRAP
1226
RAKLM
1231
IPMDA
1236
QSNNP
1241
AVVSA
1246
IPVPT
1251
LESAQ
1256
YPGIL
1261
PSPTC
1266
GYPHP
1271
QFTLR
1276
PVPFP
1281
TLSVD
1286
RGFGA
1291
GRSQS
1296
VSEGP
1301
TTQQP
1306
PMLPP
1311
SQPEH
1316
SSSEE
1321
APSRT
1326
IPTAC
1331
VRPTH
1336
PLRSF
1341
ANPLL
1346
PPPMS
1351
AIEPK
1356
VPYTP
1361
LLSQP
1366
GPTLP
1371
KTHVK
1376
TASLG
1381
LAGKA
1386
RSPLL
1391
PVSVP
1396
TAPEV
1401
SEESH
1406
KPTED
1411
SANVY
1416
EQDDL
1421
SEQMA
1426
SLEGL
1431
MKQLN
1436
AITGS
1441
AF
1446
Mutation Information
DNA mutation:
None
Peptide Range:
725 ~ 749
Mut AA position:
737 (13 in Wild Type peptide)
Alignment
Wild Type:
"VPDQPSSLHVRPQTNCIIMSWTPPL
||||||||||||.||||||||||||
Mutant:
VPDQPSSLHVRPKTNCIIMSWTPPL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) DCC
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay