Immunogenicity 9036

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF585B
Transcript ID
NM_152279
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (769 aa)
MPASW
1
TSPQK
6
SSALA
11
PEDHG
16
SSYEG
21
SVSFR
26
DVAID
31
FSREE
36
WRHLD
41
LSQRN
46
LYRDV
51
MLETY
56
SHLLS
61
VGYQV
66
PKPEV
71
VMLEQ
76
GKEPW
81
ALQGE
86
RPRHS
91
CPGEK
96
LWDHN
101
QHRKI
106
IGYKP
111
ASSQD
116
QKIYS
121
GEKSY
126
ECAEF
131
GKSFT
136
WKSQF
141
KVHLK
146
VPTGE
151
KLYVC
156
IECGR
161
AFVQK
166
PEFIT
171
HQKTH
176
MREKP
181
YKCNE
186
CGKSF
191
FQVSS
196
LFRHH
201
RIHTG
206
EKLYE
211
CSECG
216
KGFPY
221
NSDLS
226
IHEKI
231
HTGER
236
HHECT
241
DCGKA
246
FTQKS
251
TLKIH
256
QKIHT
261
GERSY
266
ICIEC
271
GQAFI
276
QKTQL
281
IAHRR
286
IHSGE
291
KPYEC
296
NNCGK
301
SFISK
306
SQLQV
311
HQRVH
316
TRVKP
321
YICTE
326
YGKVF
331
SNNSN
336
LITHE
341
KIQSR
346
EKSSI
351
CTECG
356
KAFTY
361
RSELI
366
IHQRI
371
HTGEK
376
PYECS
381
DCGRA
386
FTQKS
391
ALTVH
396
QRIHT
401
GEKSY
406
ICMKC
411
GLAFI
416
RKAHL
421
ITHQI
426
IHTGE
431
KPYKC
436
GHCGK
441
LFTSK
446
SQLHV
451
HKRIH
456
TGEKP
461
YVCNK
466
CGKAF
471
TNRSN
476
LITHQ
481
KTHTG
486
EKSYI
491
CSKCG
496
KAFTQ
501
RSDLI
506
THQRI
511
HTGEK
516
PYECN
521
TCGKA
526
FTQKS
531
NLNIH
536
QKIHT
541
GERQY
546
ECHEC
551
GKAFN
556
QKSIL
561
IVHQK
566
IHTGE
571
KPYVC
576
TECGR
581
AFIRK
586
SNFIT
591
HQRIH
596
TGEKP
601
YECSD
606
CGKSF
611
TSKSQ
616
LLVHQ
621
PVHTG
626
EKPYV
631
CAECG
636
KAFSG
641
RSNLS
646
KHQKT
651
HTGEK
656
PYICS
661
ECGKT
666
FRQKS
671
ELITH
676
HRIHT
681
GEKPY
686
ECSDC
691
GKSFT
696
KKSQL
701
QVHQR
706
IHTGE
711
KPYVC
716
AECGK
721
AFSNR
726
SNLNK
731
HQTTH
736
TGDKP
741
YKCGI
746
CGKGF
751
VQKSV
756
FSVHQ
761
SSHA
766
Mutation Information
DNA mutation:
None
Peptide Range:
635 ~ 659
Mut AA position:
647 (13 in Wild Type peptide)
Alignment
Wild Type:
"VCAECGKAFSGRSNLSKHQKTHTGE
||||||||||||.||||||||||||
Mutant:
VCAECGKAFSGRANLSKHQKTHTGE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF585B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay