Immunogenicity 9040
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ANKLE1
Transcript ID
NM_001278444
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (651 aa)
MWTPV
1
RRGAA
6
WLGTL
11
LGPGE
16
GPPEP
21
RGGAA
26
HAHKP
31
PAGSR
36
KSTDQ
41
AVRFG
46
PSQGM
51
CSEAR
56
LARRL
61
RDALR
66
EEEPW
71
AVEEL
76
LRCGA
81
DPNLV
86
LEDGA
91
AAVHL
96
AAGAR
101
HPRGL
106
RCLGA
111
LLRQG
116
GDPNA
121
RSVEA
126
LTPLH
131
VAAAW
136
GCRRG
141
LELLL
146
SQGAD
151
PALRD
156
QDGLR
161
PLDLA
166
LQQGH
171
LECAR
176
VLQDL
181
DTRTR
186
TRTRI
191
GAETQ
196
EPEPA
201
PGTPG
206
LSGPT
211
DETLD
216
SIALQ
221
KQPCR
226
GDNRD
231
IGLEA
236
DPGPP
241
SLPVP
246
LETVD
251
KHGSS
256
ASPPG
261
HWDYS
266
SDASF
271
VTAVE
276
VSGAE
281
DPASD
286
TPPWA
291
GSLPP
296
TRQGL
301
LHVVH
306
ANQRV
311
PRSQG
316
TEAEL
321
NARLQ
326
ALTLT
331
PPNAA
336
GFQSS
341
PSSMP
346
LLDRS
351
PAHSP
356
PRTPT
361
PGASD
366
CHCLW
371
EHQTS
376
IDSDM
381
ATLWL
386
TEDEA
391
SSTGG
396
REPVG
401
PCRHL
406
PVSTV
411
SDLEL
416
LKGLR
421
ALGPE
426
FSGHS
431
LELAA
436
ALRTG
441
CIPDV
446
QADED
451
ALAQQ
456
FEQPD
461
PARRW
466
REGVV
471
KSSFT
476
YLLLD
481
PRETQ
486
DLPAR
491
AFSLT
496
PAERL
501
QTFIR
506
AIFYV
511
GKGTR
516
ARPYV
521
HLWEA
526
LGHHG
531
RSRKQ
536
GSRRS
541
PTRSK
546
GTAME
551
WWQAG
556
HLLVA
561
GAWGC
566
TCCTV
571
PSLSS
576
WLKAS
581
DSFIP
586
RTSRP
591
GAECW
596
GVGHP
601
AWGEM
606
FECSS
611
CPMLT
616
AAPIS
621
GFRRG
626
VCVCV
631
CVCVC
636
VCVCL
641
CVCVC
646
V
651
Mutation Information
DNA mutation:
None
Peptide Range:
626 ~ 650
Mut AA position:
638 (13 in Wild Type peptide)
Alignment
Wild Type:
"GFRRGVCVCVCVCVCVCVCLCVCVC
||||||||||||.||||||||||||
Mutant:
GFRRGVCVCVCVFVCVCVCLCVCVC"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ANKLE1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay