Immunogenicity 9047

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
ADAM30
Transcript ID
NM_021794
HLA INFO
C*03:02
TCR INFO

No TCR info found!

T cell Tumor cell C*03:02
sequence
Full length protein sequence (790 aa)
MRSVQ
1
IFLSQ
6
CRLLL
11
LLVPT
16
MLLKS
21
LGEDV
26
IFHPE
31
GEFDS
36
YEVTI
41
PEKLS
46
FRGEV
51
QGVVS
56
PVSYL
61
LQLKG
66
KKHVL
71
HLWPK
76
RLLLP
81
RHLRV
86
FSFTE
91
HGELL
96
EDHPY
101
IPKDC
106
NYMGS
111
VKESL
116
DSKAT
121
ISTCM
126
GGLRG
131
VFNID
136
AKHYQ
141
IEPLK
146
ASPSF
151
EHVVY
156
LLKKE
161
QFGNQ
166
VCGLS
171
DDEIE
176
WQMAP
181
YENKA
186
RLRDF
191
PGSYK
196
HPKYL
201
ELILL
206
FDQSR
211
YRFVN
216
NNLSQ
221
VIHDA
226
ILLTG
231
IMDTY
236
FQDVR
241
MRIHL
246
KALEV
251
WTDFN
256
KIRVG
261
YPELA
266
EVLGR
271
FVIYK
276
KSVLN
281
ARLSS
286
DWAHL
291
YLQRK
296
YNDAL
301
AWSFG
306
KVCSL
311
EYAGS
316
VSTLL
321
DTNIL
326
APATW
331
SAHEL
336
GHAVG
341
MSHDE
346
QYCQC
351
RGRLN
356
CIMGS
361
GRTGF
366
SNCSY
371
ISFFK
376
HISSG
381
ATCLN
386
NIPGL
391
GYVLK
396
RCGNK
401
IVEDN
406
EECDC
411
GSTEE
416
CQKDR
421
CCQSN
426
CKLQP
431
GANCS
436
IGLCC
441
HDCRF
446
RPSGY
451
VCRQE
456
GNECD
461
LAEYC
466
DGNSS
471
SCPND
476
VYKQD
481
GTPCK
486
YEGRC
491
FRKGC
496
RSRYM
501
QCQSI
506
FGPDA
511
MEAPS
516
ECYDA
521
VNLIG
526
DQFGN
531
CEITG
536
IRNFK
541
KCESA
546
NSICG
551
RLQCI
556
NVETI
561
PDLPE
566
HTTII
571
STHLQ
576
AENLM
581
CWGTG
586
YHLSM
591
KPMGI
596
PDLGM
601
INDGT
606
SCGEG
611
RVCFK
616
KNCVN
621
SSVLQ
626
FDCLP
631
EKCNT
636
RGVCN
641
NRKNC
646
HCMYG
651
WAPPF
656
CEEVG
661
YGGSI
666
DSGPP
671
GLLRG
676
AIPSS
681
IWVVS
686
IIMFR
691
LILLI
696
LSVVF
701
VFFRQ
706
VIGNH
711
LKPKQ
716
EKMPL
721
SKAKT
726
EQEES
731
KTKTV
736
QEESK
741
TKTGQ
746
EESEA
751
KTGQE
756
ESKAK
761
TGQEE
766
SKANI
771
ESKRP
776
KAKSV
781
KKQKK
786
Mutation Information
DNA mutation:
None
Peptide Range:
120 ~ 144
Mut AA position:
132 (13 in Wild Type peptide)
Alignment
Wild Type:
"LDSKATISTCMGGLRGVFNIDAKHY
||||||||||||.||||||||||||
Mutant:
LDSKATISTCMGCLRGVFNIDAKHY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADAM30

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay