Immunogenicity 9073

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PRB4
Transcript ID
NM_002723
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (247 aa)
MLLIL
1
LSVAL
6
LALSS
11
AESSS
16
EDVSQ
21
EESLF
26
LISGK
31
PEGRR
36
PQGGN
41
QPQRP
46
PPPPG
51
KPQGP
56
PPQGG
61
NQSQG
66
PPPPP
71
GKPEG
76
RPPQG
81
GNQSQ
86
GPPPH
91
PGKPE
96
RPPPQ
101
GGNQS
106
QGTPP
111
PPGKP
116
ERPPP
121
QGGNQ
126
SHRPP
131
PPPGK
136
PERPP
141
PQGGN
146
QSQGP
151
PPHPG
156
KPEGP
161
PPQEG
166
NKSRS
171
ARSPP
176
GKPQG
181
PPQQE
186
GNKPQ
191
GPPPP
196
GKPQG
201
PPPAG
206
GNPQQ
211
PQAPP
216
AGKPQ
221
GPPPP
226
PQGGR
231
PPRPA
236
QGQQP
241
PQ
246
Mutation Information
DNA mutation:
None
Peptide Range:
59 ~ 83
Mut AA position:
71 (13 in Wild Type peptide)
Alignment
Wild Type:
"GPPPQGGNQSQGPPPPPGKPEGRPP
||||||||||||.||||||||||||
Mutant:
GPPPQGGNQSQGTPPPPGKPEGRPP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRB4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay