Immunogenicity 9082

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KLHDC7A
Transcript ID
NM_152375
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (777 aa)
MFPRG
1
AEAQD
6
WHLDM
11
QLTGK
16
VVLSA
21
AALLL
26
VTVAY
31
RLYKS
36
RPAPA
41
QRWGG
46
NGQAE
51
AKEEA
56
EGSGQ
61
PAVQE
66
ASPGV
71
LLRGP
76
RRRRS
81
SKRAE
86
APQGC
91
SCENP
96
RGPYV
101
LVTGA
106
TSTDR
111
KPQRK
116
GSGEE
121
RGGQG
126
SDSEQ
131
VPPCC
136
PSQET
141
RTAVG
146
SNPDP
151
PHFPR
156
LGSEP
161
KSSPA
166
GLIAA
171
ADGSC
176
AGGEP
181
SPWQD
186
SKPRE
191
HPGLG
196
QLEPP
201
HCHYV
206
APLQG
211
SSDMN
216
QSWVF
221
TRVIG
226
VSREE
231
AGALE
236
AASDV
241
DLTLH
246
QQEGA
251
PNSSY
256
TFSSI
261
ARVRM
266
EEHFI
271
QKAEG
276
VEPRL
281
KGKVY
286
DYYVE
291
STSQA
296
IFQGR
301
LAPRT
306
AALTE
311
VPSPR
316
PPPGS
321
LGTGA
326
ASGGQ
331
AGDTK
336
GAAER
341
AASPQ
346
TGPWP
351
STRGF
356
SRKES
361
LLQIA
366
ENPEL
371
QLQPD
376
GFRLP
381
APPCP
386
DPGAL
391
PGLGR
396
SSREP
401
HVQPV
406
AGTNF
411
FHIPL
416
TPASA
421
PQVRL
426
DLGNC
431
YEVLT
436
LAKRQ
441
NLEAL
446
KEAAY
451
KVMSE
456
NYLQV
461
LRSPD
466
IYGCL
471
SGAER
476
ELILQ
481
RRLRG
486
RQYLV
491
VADVC
496
PKEDS
501
GGLCC
506
YDDEQ
511
DVWRP
516
LARMP
521
PEAVS
526
RGCAI
531
CSLFN
536
YLFVV
541
SGCQG
546
PGHQP
551
SSRVF
556
CYNPL
561
TGIWS
566
EVCPL
571
NQARP
576
HCRLV
581
ALDGH
586
LYAIG
591
GECLN
596
SVERY
601
DPRLD
606
RWDFA
611
PPLPS
616
DTFAL
621
AHTAT
626
VRAKE
631
IFVTG
636
GSLRF
641
LLFRF
646
SAQEQ
651
RWWAG
656
PTGGS
661
KDRTA
666
EMVAV
671
NGFLY
676
RFDLN
681
RSLGI
686
AVYRC
691
SASTR
696
LWYEC
701
ATYRT
706
PYPDA
711
FQCAV
716
VDNLI
721
YCVGR
726
RSTLC
731
FLADS
736
VSPRF
741
VPKEL
746
RSFPA
751
PQGTL
756
LPTVL
761
TLPTP
766
DLPQT
771
RV
776
Mutation Information
DNA mutation:
None
Peptide Range:
515 ~ 539
Mut AA position:
527 (13 in Wild Type peptide)
Alignment
Wild Type:
"QDVWRPLARMPPEAVSRGCAICSLF
||||||||||||.||||||||||||
Mutant:
QDVWRPLARMPPKAVSRGCAICSLF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KLHDC7A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay