Immunogenicity 9095

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CHGB
Transcript ID
NM_001819
HLA INFO
A*30:02
TCR INFO

No TCR info found!

T cell Tumor cell A*30:02
sequence
Full length protein sequence (677 aa)
MQPTL
1
LLSLL
6
GAVGL
11
AAVNS
16
MPVDN
21
RNHNE
26
GMVTR
31
CIIEV
36
LSNAL
41
SKSSA
46
PPITP
51
ECRQV
56
LKTSR
61
KDVKD
66
KETTE
71
NENTK
76
FEVRL
81
LRDPA
86
DASEA
91
HESSS
96
RGEAG
101
APGEE
106
DIQGP
111
TKADT
116
EKWAE
121
GGGHS
126
RERAD
131
EPQWS
136
LYPSD
141
SQVSE
146
EVKTR
151
HSEKS
156
QREDE
161
EEEEG
166
ENYQK
171
GERGE
176
DSSEE
181
KHLEE
186
PGETQ
191
NAFLN
196
ERKQA
201
SAIKK
206
EELVA
211
RSETH
216
AAGHS
221
QEKTH
226
SREKS
231
SQESG
236
EETGS
241
QENHP
246
QESKG
251
QPRSQ
256
EESEE
261
GEEDA
266
TSEVD
271
KRRTR
276
PRHHH
281
GRSRP
286
DRSSQ
291
GGSLP
296
SEEKG
301
HPQEE
306
SEESN
311
VSMAS
316
LGEKR
321
DHHST
326
HYRAS
331
EEEPE
336
YGEEI
341
KGYPG
346
VQAPE
351
DLEWE
356
RYRGR
361
GSEEY
366
RAPRP
371
QSEES
376
WDEED
381
KRNYP
386
SLELD
391
KMAHG
396
YGEES
401
EEERG
406
LEPGK
411
GRHHR
416
GRGGE
421
PRAYF
426
MSDTR
431
EEKRF
436
LGEGH
441
HRVQE
446
NQMDK
451
ARRHP
456
QGAWK
461
ELDRN
466
YLNYG
471
EEGAP
476
GKWQQ
481
QGDLQ
486
DTKEN
491
REEAR
496
FQDKQ
501
YSSHH
506
TAEKR
511
KRLGE
516
LFNPY
521
YDPLQ
526
WKSSH
531
FERRD
536
NMNDN
541
FLEGE
546
EENEL
551
TLNEK
556
NFFPE
561
YNYDW
566
WEKKP
571
FSEDV
576
NWGYE
581
KRNLA
586
RVPKL
591
DLKRQ
596
YDRVA
601
QLDQL
606
LHYRK
611
KSAEF
616
PDFYD
621
SEEPV
626
STHQE
631
AENEK
636
DRADQ
641
TVLTE
646
DEKKE
651
LENLA
656
AMDLE
661
LQKIA
666
EKFSQ
671
RG
676
Mutation Information
DNA mutation:
None
Peptide Range:
215 ~ 239
Mut AA position:
227 (13 in Wild Type peptide)
Alignment
Wild Type:
"ARSETHAAGHSQEKTHSREKSSQES
||||||||||||.||||||||||||
Mutant:
ARSETHAAGHSQVKTHSREKSSQES"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CHGB

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay