Immunogenicity 9121

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
CDH4
Transcript ID
NM_001252339
HLA INFO
B*40:01
TCR INFO

No TCR info found!

T cell Tumor cell B*40:01
sequence
Full length protein sequence (842 aa)
MDFKV
1
GADGT
6
VFATR
11
ELQVP
16
SEQVA
21
FTVTA
26
WDSQT
31
AEKWD
36
AVVRL
41
LVAQT
46
SSPHS
51
GHKPQ
56
KGKKV
61
VALDP
66
SPPPK
71
DTLLP
76
WPQHQ
81
NANGL
86
RRRKR
91
DWVIP
96
PINVP
101
ENSRG
106
PFPQQ
111
LVRIR
116
SDKDN
121
DIPIR
126
YSITG
131
VGADQ
136
PPMEV
141
FSIDS
146
MSGRM
151
YVTRP
156
MDREE
161
HASYH
166
LRAHA
171
VDMNG
176
NKVEN
181
PIDLY
186
IYVID
191
MNDNR
196
PEFIN
201
QVYNG
206
SVDEG
211
SKPGT
216
YVMTV
221
TANDA
226
DDSTT
231
ANGMV
236
RYRIV
241
TQTPQ
246
SPSQN
251
MFTIN
256
SETGD
261
IVTVA
266
AGLDR
271
EKVQQ
276
YTVIV
281
QATDM
286
EGNLN
291
YGLSN
296
TATAI
301
ITVTD
306
VNDNP
311
PEFTA
316
STFAG
321
EVPEN
326
RVETV
331
VANLT
336
VMDRD
341
QPHSP
346
NWNAV
351
YRIIS
356
GDPSG
361
HFSVR
366
TDPVT
371
NEGMV
376
TVVKA
381
VDYEL
386
NRAFM
391
LTVMV
396
SNQAP
401
LASGI
406
QMSFQ
411
STAGV
416
TISIM
421
DINEA
426
PYFPS
431
NHKLI
436
RLEEG
441
VPPGT
446
VLTTF
451
SAVDP
456
DRFMQ
461
QAVRY
466
SKLSD
471
PASWL
476
HINAT
481
NGQIT
486
TAAVL
491
DRESL
496
YTKNN
501
VYEAT
506
FLAAD
511
NGIPP
516
ASGTG
521
TLQIY
526
LIDIN
531
DNAPE
536
LLPKE
541
AQICE
546
KPNLN
551
AINIT
556
AADAD
561
VDPNI
566
GPYVF
571
ELPFV
576
PAAVR
581
KNWTI
586
TRLNG
591
DYAQL
596
SLRIL
601
YLEAG
606
MYDVP
611
IIVTD
616
SGNPP
621
LSNTS
626
IIKVK
631
VCPCD
636
DNGDC
641
TTIGA
646
VAAAG
651
LGTGA
656
IVAIL
661
ICILI
666
LLTMV
671
LLFVM
676
WMKRR
681
EKERH
686
TKQLL
691
IDPED
696
DVRDN
701
ILKYD
706
EEGGG
711
EEDQD
716
YDLSQ
721
LQQPE
726
AMGHV
731
PSKAP
736
GVRRV
741
DERPV
746
GAEPQ
751
YPIRP
756
MVPHP
761
GDIGD
766
FINEG
771
LRAAD
776
NDPTA
781
PPYDS
786
LLVFD
791
YEGSG
796
STAGS
801
VSSLN
806
SSSSG
811
DQDYD
816
YLNDW
821
GPRFK
826
KLADM
831
YGGGE
836
ED
841
Mutation Information
DNA mutation:
None
Peptide Range:
513 ~ 537
Mut AA position:
525 (13 in Wild Type peptide)
Alignment
Wild Type:
"AADNGIPPASGTGTLQIYLIDINDN
||||||||||||.||||||||||||
Mutant:
AADNGIPPASGTRTLQIYLIDINDN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CDH4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay