Immunogenicity 9151

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CDH4
Transcript ID
NM_001794
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (916 aa)
MTAGA
1
GVLLL
6
LLSLS
11
GALRA
16
HNEDL
21
TTRET
26
CKAGF
31
SEDDY
36
TALIS
41
QNILE
46
GEKLL
51
QVKFS
56
SCVGT
61
KGTQY
66
ETNSM
71
DFKVG
76
ADGTV
81
FATRE
86
LQVPS
91
EQVAF
96
TVTAW
101
DSQTA
106
EKWDA
111
VVRLL
116
VAQTS
121
SPHSG
126
HKPQK
131
GKKVV
136
ALDPS
141
PPPKD
146
TLLPW
151
PQHQN
156
ANGLR
161
RRKRD
166
WVIPP
171
INVPE
176
NSRGP
181
FPQQL
186
VRIRS
191
DKDND
196
IPIRY
201
SITGV
206
GADQP
211
PMEVF
216
SIDSM
221
SGRMY
226
VTRPM
231
DREEH
236
ASYHL
241
RAHAV
246
DMNGN
251
KVENP
256
IDLYI
261
YVIDM
266
NDNRP
271
EFINQ
276
VYNGS
281
VDEGS
286
KPGTY
291
VMTVT
296
ANDAD
301
DSTTA
306
NGMVR
311
YRIVT
316
QTPQS
321
PSQNM
326
FTINS
331
ETGDI
336
VTVAA
341
GLDRE
346
KVQQY
351
TVIVQ
356
ATDME
361
GNLNY
366
GLSNT
371
ATAII
376
TVTDV
381
NDNPP
386
EFTAS
391
TFAGE
396
VPENR
401
VETVV
406
ANLTV
411
MDRDQ
416
PHSPN
421
WNAVY
426
RIISG
431
DPSGH
436
FSVRT
441
DPVTN
446
EGMVT
451
VVKAV
456
DYELN
461
RAFML
466
TVMVS
471
NQAPL
476
ASGIQ
481
MSFQS
486
TAGVT
491
ISIMD
496
INEAP
501
YFPSN
506
HKLIR
511
LEEGV
516
PPGTV
521
LTTFS
526
AVDPD
531
RFMQQ
536
AVRYS
541
KLSDP
546
ASWLH
551
INATN
556
GQITT
561
AAVLD
566
RESLY
571
TKNNV
576
YEATF
581
LAADN
586
GIPPA
591
SGTGT
596
LQIYL
601
IDIND
606
NAPEL
611
LPKEA
616
QICEK
621
PNLNA
626
INITA
631
ADADV
636
DPNIG
641
PYVFE
646
LPFVP
651
AAVRK
656
NWTIT
661
RLNGD
666
YAQLS
671
LRILY
676
LEAGM
681
YDVPI
686
IVTDS
691
GNPPL
696
SNTSI
701
IKVKV
706
CPCDD
711
NGDCT
716
TIGAV
721
AAAGL
726
GTGAI
731
VAILI
736
CILIL
741
LTMVL
746
LFVMW
751
MKRRE
756
KERHT
761
KQLLI
766
DPEDD
771
VRDNI
776
LKYDE
781
EGGGE
786
EDQDY
791
DLSQL
796
QQPEA
801
MGHVP
806
SKAPG
811
VRRVD
816
ERPVG
821
AEPQY
826
PIRPM
831
VPHPG
836
DIGDF
841
INEGL
846
RAADN
851
DPTAP
856
PYDSL
861
LVFDY
866
EGSGS
871
TAGSV
876
SSLNS
881
SSSGD
886
QDYDY
891
LNDWG
896
PRFKK
901
LADMY
906
GGGEE
911
D
916
Mutation Information
DNA mutation:
None
Peptide Range:
503 ~ 527
Mut AA position:
515 (13 in Wild Type peptide)
Alignment
Wild Type:
"EAPYFPSNHKLIRLEEGVPPGTVLT
||||||||||||.||||||||||||
Mutant:
EAPYFPSNHKLIHLEEGVPPGTVLT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CDH4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay