Immunogenicity 9159
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LMTK3
Transcript ID
NM_001080434
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (1489 aa)
MRQVL
1
WLCNV
6
CVTAR
11
ETRHH
16
LHLPA
21
ILDKM
26
PAPGA
31
LILLA
36
AVSAS
41
GCLAS
46
PAHPD
51
GFALG
56
RAPLA
61
PPYAV
66
VLISC
71
SGLLA
76
FIFLL
81
LTCLC
86
CKRGD
91
VGFKE
96
FENPE
101
GEDCS
106
GEYTP
111
PAEET
116
SSSQS
121
LPDVY
126
ILPLA
131
EVSLP
136
MPAPQ
141
PSHSD
146
MTTPL
151
GLSRQ
156
HLSYL
161
QEIGS
166
GWFGK
171
VILGE
176
IFSDY
181
TPAQV
186
VVKEL
191
RASAG
196
PLEQR
201
KFISE
206
AQPYR
211
SLQHP
216
NVLQC
221
LGLCV
226
ETLPF
231
LLIME
236
FCQLG
241
DLKRY
246
LRAQR
251
PPEGL
256
SPELP
261
PRDLR
266
TLQRM
271
GLEIA
276
RGLAH
281
LHSHN
286
YVHSD
291
LALRN
296
CLLTS
301
DLTVR
306
IGDYG
311
LAHSN
316
YKEDY
321
YLTPE
326
RLWIP
331
LRWAA
336
PELLG
341
ELHGT
346
FMVVD
351
QSRES
356
NIWSL
361
GVTLW
366
ELFEF
371
GAQPY
376
RHLSD
381
EEVLA
386
FVVRQ
391
QHVKL
396
ARPRL
401
KLPYA
406
DYWYD
411
ILQSC
416
WRPPA
421
QRPSA
426
SDLQL
431
QLTYL
436
LSERP
441
PRPPP
446
PPPPP
451
RDGPF
456
PWPWP
461
PAHSA
466
PRPGT
471
LSSPF
476
PLLDG
481
FPGAD
486
PDDVL
491
TVTES
496
SRGLN
501
LECLW
506
EKARR
511
GAGRG
516
GGAPA
521
WQPAS
526
APPAP
531
HANPS
536
NPFYE
541
ALSTP
546
SVLPV
551
ISARS
556
PSVSS
561
EYYIR
566
LEEHG
571
SPPEP
576
LFPND
581
WDPLD
586
PGVPA
591
PQAPQ
596
APSEV
601
PQLVS
606
ETWAS
611
PLFPA
616
PRPFP
621
AQSSA
626
SGSFL
631
LSGWD
636
PEGRG
641
AGETL
646
AGDPA
651
EVLGE
656
RGTAP
661
WVEEE
666
EEEEE
671
GSSPG
676
EDSSS
681
LGGGP
686
SRRGP
691
LPCPL
696
CSREG
701
ACSCL
706
PLERG
711
DAVAG
716
WGGHP
721
ALGCP
726
HPPED
731
DSSLR
736
AERGS
741
LADLP
746
MAPPA
751
SAPPE
756
FLDPL
761
MGAAA
766
PQYPG
771
RGPPP
776
APPPP
781
PPPPR
786
APADP
791
AASPD
796
PPSAV
801
ASPGS
806
GLSSP
811
GPKPG
816
DSGYE
821
TETPF
826
SPEGA
831
FPGGG
836
AAEEE
841
GVPRP
846
RAPPE
851
PPDPG
856
APRPP
861
PDPGP
866
LPLPG
871
PREKP
876
TFVVQ
881
VSTEQ
886
LLMSL
891
REDVT
896
RNLLG
901
EKGAT
906
ARETG
911
PRKAG
916
RGPGN
921
REKVP
926
GLNRD
931
PTVLG
936
NGKQA
941
PSLSL
946
PVNGV
951
TVLEN
956
GDQRA
961
PGIEE
966
KAAEN
971
GALGS
976
PEREE
981
KVLEN
986
GELTP
991
PRREE
996
KALEN
1001
GELRS
1006
PEAGE
1011
KVLVN
1016
GGLTP
1021
PKSED
1026
KVSEN
1031
GGLRF
1036
PRNTE
1041
RPPET
1046
GPWRA
1051
PGPWE
1056
KTPES
1061
WGPAP
1066
TIGEP
1071
APETS
1076
LERAP
1081
APSAV
1086
VSSRN
1091
GGETA
1096
PGPLG
1101
PAPKN
1106
GTLEP
1111
GTERR
1116
APETG
1121
GAPRA
1126
PGAGR
1131
LDLGS
1136
GGRAP
1141
VGTGT
1146
APGGG
1151
PGSGV
1156
DAKAG
1161
WVDNT
1166
RPQPP
1171
PPPLP
1176
PPPEA
1181
QPRRL
1186
EPAPP
1191
RARPE
1196
VAPEG
1201
EPGAP
1206
DSRAG
1211
GDTAL
1216
SGDGD
1221
PPKPE
1226
RKGPE
1231
MPRLF
1236
LDLGP
1241
PQGNS
1246
EQIKA
1251
RLSRL
1256
SLALP
1261
PLTLT
1266
PFPGP
1271
GPRRP
1276
PWEGA
1281
DAGAA
1286
GGEAG
1291
GAGAP
1296
GPAEE
1301
DGEDE
1306
DEDEE
1311
EDEEA
1316
AAPGA
1321
AAGPR
1326
GPGRA
1331
RAAPV
1336
PVVVS
1341
SADAD
1346
AARPL
1351
RGLLK
1356
SPRGA
1361
DEPED
1366
SELER
1371
KRKMV
1376
SFHGD
1381
VTVYL
1386
FDQET
1391
PTNEL
1396
SVQAP
1401
PEGDT
1406
DPSTP
1411
PAPPT
1416
PPHPA
1421
TPGDG
1426
FPSND
1431
SGFGG
1436
SFEWA
1441
EDFPL
1446
LPPPG
1451
PPLCF
1456
SRFSV
1461
SPALE
1466
TPGPP
1471
ARAPD
1476
ARPAG
1481
PVEN
1486
Mutation Information
DNA mutation:
None
Peptide Range:
473 ~ 497
Mut AA position:
485 (13 in Wild Type peptide)
Alignment
Wild Type:
"PGTLSSPFPLLDGFPGADPDDVLTV
||||||||||||.||||||||||||
Mutant:
PGTLSSPFPLLDCFPGADPDDVLTV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) LMTK3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay