Immunogenicity 9180

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
RASIP1
Transcript ID
NM_017805
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (963 aa)
MLSGE
1
RKEGG
6
SPRFG
11
KLHLP
16
VGLWI
21
NSPRK
26
QLAKL
31
GRRWP
36
SAASV
41
KSSSS
46
DTGSR
51
SSEPL
56
PPPPP
61
HVELR
66
RVGAV
71
KAAGG
76
ASGSR
81
AKRIS
86
QLFRG
91
SGTGT
96
TGSSG
101
AGGPG
106
TPGGA
111
QRWAS
116
EKKLP
121
ELAAG
126
VAPEP
131
PLATR
136
ATAPP
141
GVLKI
146
FGAGL
151
ASGAN
156
YKSVL
161
ATARS
166
TAREL
171
VAEAL
176
ERYGL
181
AGSPG
186
GGPGE
191
SSCVD
196
AFALC
201
DALGR
206
PAAAG
211
VGSGE
216
WRAEH
221
LRVLG
226
DSERP
231
LLVQE
236
LWRAR
241
PGWAR
246
RFELR
251
GREEA
256
RRLEQ
261
EAFGA
266
ADSEG
271
TGAPS
276
WRPQK
281
NRSRA
286
ASGGA
291
ALASP
296
GPGTG
301
SGAPA
306
GSGGK
311
ERSEN
316
LSLRR
321
SVSEL
326
SLQGR
331
RRRQQ
336
ERRQQ
341
ALSMA
346
PGAAD
351
AQIGT
356
ADPGD
361
FDQLT
366
QCLIQ
371
APSNR
376
PYFLL
381
LQGYQ
386
DAQDF
391
VVYVM
396
TREQH
401
VFGRG
406
GNSSG
411
RGGSP
416
APYVD
421
TFLNA
426
PDILP
431
RHCTV
436
RAGPE
441
HPAMV
446
RPSRG
451
APVTH
456
NGCLL
461
LREAE
466
LHPGD
471
LLGLG
476
EHFLF
481
MYKDP
486
RTGGS
491
GPARP
496
PWLPA
501
RPGAT
506
PPGPG
511
WAFSC
516
RLCGR
521
GLQER
526
GEALA
531
AYLDG
536
REPVL
541
RFRPR
546
EEEAL
551
LGEIV
556
RAAAA
561
GSGDL
566
PPLGP
571
ATLLA
576
LCVQH
581
SAREL
586
ELGHL
591
PRLLG
596
RLARL
601
IKEAV
606
WEKIK
611
EIGDR
616
QPENH
621
PEGVP
626
EVPLT
631
PEAVS
636
VELRP
641
LMLWM
646
ANTTE
651
LLSFV
656
QEKVL
661
EMEKE
666
ADQED
671
PQLCN
676
DLELC
681
DEAMA
686
LLDEV
691
IMCTF
696
QQSVY
701
YLTKT
706
LYSTL
711
PALLD
716
SNPFT
721
AGAEL
726
PGPGA
731
ELGAM
736
PPGLR
741
PTLGV
746
FQAAL
751
ELTSQ
756
CELHP
761
DLVSQ
766
TFGYL
771
FFFSN
776
ASLLN
781
SLMER
786
GQGRP
791
FYQWS
796
RAVQI
801
RTNLD
806
LVLDW
811
LQGAG
816
LGDIA
821
TEFFR
826
KLSMA
831
VNLLC
836
VPRTS
841
LLKAS
846
WSSLR
851
TDHPT
856
LTPAQ
861
LHHLL
866
SHYQL
871
GPGRG
876
PPAAW
881
DPPPA
886
EREAV
891
DTGDI
896
FESFS
901
SHPPL
906
ILPLG
911
SSRLR
916
LTGPV
921
TDDAL
926
HRELR
931
RLRRL
936
LWDLE
941
QQELP
946
ANYRH
951
GPPVA
956
TSP
961
Mutation Information
DNA mutation:
None
Peptide Range:
288 ~ 312
Mut AA position:
300 (13 in Wild Type peptide)
Alignment
Wild Type:
"SRAASGGAALASPGPGTGSGAPAGS
||||||||||||.||||||||||||
Mutant:
SRAASGGAALASHGPGTGSGAPAGS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RASIP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay