Immunogenicity 9188

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZBED5
Transcript ID
NM_021211
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (693 aa)
MIAPL
1
LCILS
6
YNFNT
11
FAILN
16
VYSKL
21
TMFCT
26
TNSLP
31
MDLLL
36
KQGSL
41
KQEVE
46
SFCYQ
51
IVSES
56
NDQKV
61
GILQS
66
EDKQL
71
QPSVS
76
KKSEG
81
ELSRV
86
KFISN
91
SNKIT
96
FSKKP
101
KRRKY
106
DESYL
111
SFGFT
116
YFGNR
121
DAPHA
126
QCVLC
131
KKILS
136
NSSLA
141
PSKLR
146
RHLET
151
KHAAY
156
KDKDI
161
SFFKQ
166
HLDSP
171
ENNKP
176
PTPKI
181
VNTDN
186
ESATE
191
ASYNV
196
SYHIA
201
LSGEA
206
HTIGE
211
LLIKP
216
CAKDV
221
VMRMF
226
DEQYS
231
KKIDA
236
VQLSN
241
STVAR
246
RIKDL
251
AADIE
256
EELVC
261
RLKIC
266
DGFSL
271
QLDES
276
ADVSG
281
LAVLL
286
VFVRY
291
RFNKS
296
IEEDL
301
LLCES
306
LQSNA
311
TGEEI
316
FNCIN
321
SFMQK
326
HEIEW
331
EKCVD
336
VCSDA
341
SRAVD
346
GKIAE
351
AVTLI
356
KYVAP
361
ESTSS
366
HCLLY
371
RHALA
376
VKIMP
381
TSLKN
386
VLDQA
391
VQIIN
396
YIKAR
401
PHQSR
406
LLKIL
411
CEEMG
416
AQHTA
421
LLLNT
426
EVRWL
431
SRGKV
436
LVRLF
441
ELRRE
446
LLVFM
451
DSAFR
456
LSDCL
461
TNSSW
466
LLRLA
471
YLADI
476
FTKLN
481
EVNLS
486
MQGKN
491
VTVFT
496
VFDKM
501
SSLLR
506
KLEFW
511
ASSVE
516
EENFD
521
CFPTL
526
SDFLT
531
EINST
536
VDKDI
541
CSAIV
546
QHLRG
551
LRATL
556
LKYFP
561
VTNDN
566
NAWVR
571
NPFTV
576
TVKPA
581
SLVAR
586
DYESL
591
IDLTS
596
DSQVK
601
QNFSE
606
LSLND
611
FWSSL
616
IQEYP
621
SIARR
626
AVRVL
631
LPFAT
636
MHLCE
641
TGFSY
646
YAATK
651
TKYRK
656
RLDAA
661
PHMRI
666
RLSNI
671
TPNIK
676
RICDK
681
KTQKH
686
CSH
691
Mutation Information
DNA mutation:
None
Peptide Range:
238 ~ 262
Mut AA position:
250 (13 in Wild Type peptide)
Alignment
Wild Type:
"IDAVQLSNSTVARRIKDLAADIEEE
||||||||||||.||||||||||||
Mutant:
IDAVQLSNSTVAHRIKDLAADIEEE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZBED5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay