Immunogenicity 9214

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
YAE1D1
Transcript ID
NM_001282446
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (206 aa)
MSWVQ
1
AASLI
6
QGPGD
11
KGDVF
16
DEEAD
21
ESLLA
26
QREWQ
31
SNMQR
36
RVKEG
41
YRDGI
46
DAGKA
51
VTLQQ
56
GFNQG
61
YKKGA
66
EVILN
71
YGRLR
76
GTLRN
81
STDWS
86
LLGLR
91
APLRS
96
PEVGT
101
QLLPR
106
PLPVP
111
GHMAS
116
GATPK
121
QPTEL
126
EATLL
131
SLVPQ
136
SGRAT
141
PRFPA
146
RLRAP
151
GPGTP
156
SHRRR
161
FRRKP
166
HRDPA
171
AACPA
176
WPPEA
181
PSNSE
186
THFST
191
YNRII
196
IRGGH
201
I
206
Mutation Information
DNA mutation:
None
Peptide Range:
157 ~ 181
Mut AA position:
169 (13 in Wild Type peptide)
Alignment
Wild Type:
"PGTPSHRRRFRRKPHRDPAAACPAW
||||||||||||.||||||||||||
Mutant:
PGTPSHRRRFRRNPHRDPAAACPAW"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) YAE1D1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay