Immunogenicity 9234
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF737
Transcript ID
NM_001159293
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (536 aa)
MGPLQ
1
FRDVA
6
IEFSL
11
EEWHC
16
LDTAQ
21
RNLYR
26
NVMLE
31
NYRNL
36
VFLGI
41
VVSKP
46
DLITC
51
LEQGK
56
KPLTM
61
KKHEM
66
VANPS
71
VTCSH
76
FARDL
81
WPEQS
86
IKDSF
91
QKVTL
96
RRYEN
101
YGHDN
106
LQFKK
111
GCESV
116
DECKV
121
HKRGY
126
NGLNQ
131
YLTTT
136
QSKIF
141
QCDKY
146
VKVIH
151
KFSNS
156
NRHKI
161
RHTGK
166
KPFKC
171
IECGK
176
AFNQS
181
STLTT
186
HKKIH
191
TGEKP
196
FKCEE
201
CGKAF
206
NWSSH
211
LTTHK
216
RIHTG
221
EKRYK
226
CEDCG
231
KAFSR
236
FSYLT
241
AHKII
246
HSGEK
251
PYKCE
256
ECGKA
261
FKRSS
266
NLTTH
271
KIIHT
276
GEKPY
281
KCEEC
286
GKAFK
291
RSSIL
296
TAHKI
301
IHSGE
306
KPYKC
311
EECGK
316
AFKHP
321
SVLTT
326
HKRIH
331
TGEKP
336
YKCEE
341
CGRAF
346
KYFSS
351
LTTHK
356
IIHSG
361
EKPYK
366
CEECG
371
KAFNW
376
SSHLT
381
THKRI
386
HTGEK
391
PYKCE
396
ECGEA
401
FKYSS
406
SLTTH
411
KIIHT
416
GQQPF
421
KCEEC
426
GKAFK
431
CFSIL
436
TTHKR
441
IHTGE
446
KPYKC
451
EECGK
456
AFNSS
461
SHLTA
466
HKRIH
471
TGEKP
476
YKCER
481
CGKAF
486
KRSFI
491
LTRHK
496
RIHTG
501
EKPYK
506
CEECG
511
KGFKC
516
PSTLT
521
THKVI
526
HTGEK
531
L
536
Mutation Information
DNA mutation:
None
Peptide Range:
449 ~ 478
Mut AA position:
461 (13 in Wild Type peptide)
Alignment
Wild Type:
"-----GEKPYKCEECGKAFNSSSHLTAHKR
|||||||.||||.||||||||||||
Mutant:
KRIHTGEKPYKCKECGKSFNSSSHLTAHKR"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ZNF737
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay