Immunogenicity 9312

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PNKD
Transcript ID
NM_015488
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (385 aa)
MAAVV
1
AATAL
6
KGRGA
11
RNARV
16
LRGIL
21
AGATA
26
NKASH
31
NRTRA
36
LQSHS
41
SPEGK
46
EEPEP
51
LSPEL
56
EYIPR
61
KRGKN
66
PMKAV
71
GLAWY
76
SLYTR
81
TWLGY
86
LFYRQ
91
QLRRA
96
RNRYP
101
KGHSK
106
TQPRL
111
FNGVK
116
VLPIP
121
VLSDN
126
YSYLI
131
IDTQA
136
QLAVA
141
VDPSD
146
PRAVQ
151
ASIEK
156
EGVTL
161
VAILC
166
THKHW
171
DHSGG
176
NRDLS
181
RRHRD
186
CRVYG
191
SPQDG
196
IPYLT
201
HPLCH
206
QDVVS
211
VGRLQ
216
IRALA
221
TPGHT
226
QGHLV
231
YLLDG
236
EPYKG
241
PSCLF
246
SGDLL
251
FLSGC
256
GRTFE
261
GNAET
266
MLSSL
271
DTVLG
276
LGDDT
281
LLWPG
286
HEYAE
291
ENLGF
296
AGVVE
301
PENLA
306
RERKM
311
QWVQR
316
QRLER
321
KGTCP
326
STLGE
331
ERSYN
336
PFLRT
341
HCLAL
346
QEALG
351
PGPGP
356
TGDDD
361
YSRAQ
366
LLEEL
371
RRLKD
376
MHKSK
381
Mutation Information
DNA mutation:
None
Peptide Range:
299 ~ 323
Mut AA position:
311 (13 in Wild Type peptide)
Alignment
Wild Type:
"GFAGVVEPENLARERKMQWVQRQRL
||||||||||||.||||||||||||
Mutant:
GFAGVVEPENLAQERKMQWVQRQRL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PNKD

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay