Immunogenicity 9355

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
C16orf96
Transcript ID
NM_001145011
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (1141 aa)
MSFSL
1
TFTEL
6
ANIAI
11
PQCGV
16
LNFKA
21
LHLLL
26
HGILE
31
HIHMA
36
ELKKV
41
LSGDE
46
DFLQT
51
SQVVI
56
MPREG
61
DAQPI
66
LNPMK
71
RLSNV
76
FDHVV
81
SRLDK
86
LENQL
91
ALLQD
96
LPSTA
101
QLLEA
106
SQGTA
111
RPVQD
116
LWHLI
121
KLRKM
126
VEGHD
131
EVMAK
136
SMQTL
141
QDLLT
146
DLHAL
151
QVTIT
156
ALRKE
161
VDMLK
166
NMLDK
171
VHPER
176
MDIFA
181
EDFKI
186
QNWKM
191
VALQR
196
EVASL
201
QNKFK
206
TIPKT
211
EDMVL
216
WSGLH
221
DAMFT
226
SEIGS
231
SPLDL
236
WQSVE
241
QLPEA
246
ALAQT
251
TKYLE
256
ATRAI
261
QVSEP
266
VQNPQ
271
LLQTV
276
WHYEV
281
PELLP
286
EGSSA
291
QAVSL
296
SRAQE
301
PAQPP
306
ALTPE
311
SAPGC
316
TTEFA
321
PGPAP
326
GTEPV
331
PGLEL
336
GLELE
341
PVPAL
346
GPVPG
351
PSVTP
356
GSLPA
361
PWPVL
366
GPVPA
371
PGAQP
376
PPLGD
381
WPALP
386
RRWPL
391
PQGWP
396
RVGSW
401
PLWDL
406
GVLRP
411
TQPQP
416
SRAPP
421
PATEF
426
GSLWP
431
RPLQP
436
YQSRQ
441
GEALQ
446
LAAVQ
451
VKGEE
456
NDVPS
461
LRGLR
466
ERARK
471
DGAPK
476
DRTRK
481
DGVPK
486
DRGGK
491
DVDPK
496
DRAHK
501
DDVPK
506
DRGGK
511
DVDPK
516
DRAHK
521
DDVPK
526
DRGGK
531
DGDPK
536
DRVGK
541
DGAPK
546
EAQPK
551
APQSA
556
LHRLK
561
TTAAI
566
AAAAA
571
AAYAA
576
ATSSA
581
AQAAK
586
VAAKF
591
VKDAP
596
ATKMA
601
AIATD
606
TAAAG
611
PLGVF
616
ADVLG
621
AGPSR
626
GATES
631
QILGD
636
DSEIY
641
EILSP
646
SYSAA
651
SIGPD
656
PALSQ
661
AMVAT
666
KQAMS
671
PEDKK
676
RAVKY
681
SMSHI
686
AQIPV
691
KHDSL
696
KEEFA
701
QLSCN
706
LNQRL
711
SYLAN
716
MGGPS
721
SLGTT
726
VDILQ
731
KKIGS
736
LQKSR
741
LKEEE
746
LERIW
751
GNQIE
756
MMKDR
761
YITLD
766
KAVEN
771
LQIRM
776
DEFKT
781
LQAQI
786
KRLEM
791
NKVNK
796
STMEE
801
ELREK
806
ADRSA
811
LAGKA
816
SRVDL
821
ETVAL
826
ELNEM
831
IQGIL
836
FKVTI
841
HEDSW
846
KKAME
851
ELSKD
856
VNTKL
861
VHSDL
866
DPLKK
871
EMEEV
876
WKIVR
881
KLLIE
886
GLRLD
891
PDSAA
896
GFRRK
901
LFKRV
906
KCISC
911
DRPVE
916
MMTGP
921
QLITI
926
RKAHL
931
LSRLR
936
PASAN
941
SCEYL
946
QRQQM
951
REQQW
956
LQLQD
961
LGIQE
966
DCQQD
971
WGDGP
976
QNATS
981
LKCKS
986
CNLLT
991
LYPYG
996
DPHVI
1001
DYDSA
1006
EVDIL
1011
GVDGI
1016
LYKGR
1021
VNSQR
1026
GAQPL
1031
AVAKE
1036
LAAVK
1041
APSPP
1046
SQSLY
1051
DRVHS
1056
SALFG
1061
AICPP
1066
LCPRS
1071
SACSA
1076
ASGPH
1081
LTMPA
1086
RPPSL
1091
PPLLL
1096
LPPLI
1101
PSLRD
1106
PQQAP
1111
GSTRL
1116
SRAPH
1121
IESRV
1126
GRKPP
1131
EEPAN
1136
P
1141
Mutation Information
DNA mutation:
None
Peptide Range:
569 ~ 593
Mut AA position:
581 (13 in Wild Type peptide)
Alignment
Wild Type:
"AIAAAAAAAYAAATSSAAQAAKVAA
||||||||||||.||||||||||||
Mutant:
AIAAAAAAAYAAVTSSAAQAAKVAA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) C16orf96

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay