Immunogenicity 9377
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TNXB
Transcript ID
NM_019105
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (4242 aa)
MMPAQ
1
YALTS
6
SLVLL
11
VLLST
16
ARAGP
21
FSSRS
26
NVTLP
31
APRPP
36
PQPGG
41
HTVGA
46
GVGSP
51
SSQLY
56
EHTVE
61
GGEKQ
66
VVFTH
71
RINLP
76
PSTGC
81
GCPPG
86
TEPPV
91
LASEV
96
QALRV
101
RLEIL
106
EELVK
111
GLKEQ
116
CTGGC
121
CPASA
126
QAGTG
131
QTDVR
136
TLCSL
141
HGVFD
146
LSRCT
151
CSCEP
156
GWGGP
161
TCSDP
166
TDAEI
171
PPSSP
176
PSASG
181
SCPDD
186
CNDQG
191
RCVRG
196
RCVCF
201
PGYTG
206
PSCGW
211
PSCPG
216
DCQGR
221
GRCVQ
226
GVCVC
231
RAGFS
236
GPDCS
241
QRSCP
246
RGCSQ
251
RGRCE
256
GGRCV
261
CDPGY
266
TGDDC
271
GMRSC
276
PRGCS
281
QRGRC
286
ENGRC
291
VCNPG
296
YTGED
301
CGVRS
306
CPRGC
311
SQRGR
316
CKDGR
321
CVCDP
326
GYTGE
331
DCGTR
336
SCPWD
341
CGEGG
346
RCVDG
351
RCVCW
356
PGYTG
361
EDCST
366
RTCPR
371
DCRGR
376
GRCED
381
GECIC
386
DTGYS
391
GDDCG
396
VRSCP
401
GDCNQ
406
RGRCE
411
DGRCV
416
CWPGY
421
TGTDC
426
GSRAC
431
PRDCR
436
GRGRC
441
ENGVC
446
VCNAG
451
YSGED
456
CGVRS
461
CPGDC
466
RGRGR
471
CESGR
476
CMCWP
481
GYTGR
486
DCGTR
491
ACPGD
496
CRGRG
501
RCVDG
506
RCVCN
511
PGFTG
516
EDCGS
521
RRCPG
526
DCRGH
531
GLCED
536
GVCVC
541
DAGYS
546
GEDCS
551
TRSCP
556
GGCRG
561
RGQCL
566
DGRCV
571
CEDGY
576
SGEDC
581
GVRQC
586
PNDCS
591
QHGVC
596
QDGVC
601
ICWEG
606
YVSED
611
CSIRT
616
CPSNC
621
HGRGR
626
CEEGR
631
CLCDP
636
GYTGP
641
TCATR
646
MCPAD
651
CRGRG
656
RCVQG
661
VCLCH
666
VGYGG
671
EDCGQ
676
EEPPA
681
SACPG
686
GCGPR
691
ELCRA
696
GQCVC
701
VEGFR
706
GPDCA
711
IQTCP
716
GDCRG
721
RGECH
726
DGSCV
731
CKDGY
736
AGEDC
741
GEEVP
746
TIEGM
751
RMHLL
756
EETTV
761
RTEWT
766
PAPGP
771
VDAYE
776
IQFIP
781
TTEGA
786
SPPFT
791
ARVPS
796
SASAY
801
DQRGL
806
APGQE
811
YQVTV
816
RALRG
821
TSWGL
826
PASKT
831
ITTMI
836
DGPQD
841
LRVVA
846
VTPTT
851
LELGW
856
LRPQA
861
EVDRF
866
VVSYV
871
SAGNQ
876
RVRLE
881
VPPEA
886
DGTLL
891
TDLMP
896
GVEYV
901
VTVTA
906
ERGRA
911
VSYPA
916
SVRAN
921
TGSSP
926
LGLLG
931
TTDEP
936
PPSGP
941
STTQG
946
AQAPL
951
LQQRP
956
QELGE
961
LRVLG
966
RDETG
971
RLRVV
976
WTAQP
981
DTFAY
986
FQLRM
991
RVPEG
996
PGAHE
1001
EVLPG
1006
DVRQA
1011
LVPPP
1016
PPGTP
1021
YELSL
1026
HGVPP
1031
GGKPS
1036
DPIIY
1041
QGIMD
1046
KDEEK
1051
PGKSS
1056
GPPRL
1061
GELTV
1066
TDRTS
1071
DSLLL
1076
RWTVP
1081
EGEFD
1086
SFVIQ
1091
YKDRD
1096
GQPQV
1101
VPVEG
1106
PQRSA
1111
VITSL
1116
DPGRK
1121
YKFVL
1126
YGFVG
1131
KKRHG
1136
PLVAE
1141
AKILP
1146
QSDPS
1151
PGTPP
1156
HLGNL
1161
WVTDP
1166
TPDSL
1171
HLSWT
1176
VPEGQ
1181
FDTFM
1186
VQYRD
1191
RDGRP
1196
QVVPV
1201
EGPER
1206
SFVVS
1211
SLDPD
1216
HKYRF
1221
TLFGI
1226
ANKKR
1231
YGPLT
1236
ADGTT
1241
APERK
1246
EEPPR
1251
PEFLE
1256
QPLLG
1261
ELTVT
1266
GVTPD
1271
SLRLS
1276
WTVAQ
1281
GPFDS
1286
FMVQY
1291
KDAQG
1296
QPQAV
1301
PVAGD
1306
ENEVT
1311
VPGLD
1316
PDRKY
1321
KMNLY
1326
GLRGR
1331
QRVGP
1336
ESVVA
1341
KTAPQ
1346
EDVDE
1351
TPSPT
1356
ELGTE
1361
APESP
1366
EEPLL
1371
GELTV
1376
TGSSP
1381
DSLSL
1386
FWTVP
1391
QGSFD
1396
SFTVQ
1401
YKDRD
1406
GRPRA
1411
VRVGG
1416
KESEV
1421
TVGGL
1426
EPGHK
1431
YKMHL
1436
YGLHE
1441
GQRVG
1446
PVSAV
1451
GVTAP
1456
QQEET
1461
PPATE
1466
SPLEP
1471
RLGEL
1476
TVTDV
1481
TPNSV
1486
GLSWT
1491
VPEGQ
1496
FDSFI
1501
VQYKD
1506
KDGQP
1511
QVVPV
1516
AADQR
1521
EVTVY
1526
NLEPE
1531
RKYKM
1536
NMYGL
1541
HDGQR
1546
MGPLS
1551
VVIVT
1556
APLPP
1561
APATE
1566
ASKPP
1571
LEPRL
1576
GELTV
1581
TDITP
1586
DSVGL
1591
SWTVP
1596
EGEFD
1601
SFVVQ
1606
YKDRD
1611
GQPQV
1616
VPVAA
1621
DQREV
1626
TIPDL
1631
EPSRK
1636
YKFLL
1641
FGIQD
1646
GKRRS
1651
PVSVE
1656
AKTVA
1661
RGDAS
1666
PGAPP
1671
RLGEL
1676
WVTDP
1681
TPDSL
1686
RLSWT
1691
VPEGQ
1696
FDSFV
1701
VQFKD
1706
KDGPQ
1711
VVPVE
1716
GHERS
1721
VTVTP
1726
LDAGR
1731
KYRFL
1736
LYGLL
1741
GKKRH
1746
GPLTA
1751
DGTTE
1756
ARSAM
1761
DDTGT
1766
KRPPK
1771
PRLGE
1776
ELQVT
1781
TVTQN
1786
SVGLS
1791
WTVPE
1796
GQFDS
1801
FVVQY
1806
KDRDG
1811
QPQVV
1816
PVEGS
1821
LREVS
1826
VPGLD
1831
PAHRY
1836
KLLLY
1841
GLHHG
1846
KRVGP
1851
ISAVA
1856
ITAGR
1861
EETET
1866
ETTAP
1871
TPPAP
1876
EPHLG
1881
ELTVE
1886
EATSH
1891
TLHLS
1896
WMVTE
1901
GEFDS
1906
FEIQY
1911
TDRDG
1916
QLQMV
1921
RIGGD
1926
RNDIT
1931
LSGLE
1936
SDHRY
1941
LVTLY
1946
GFSDG
1951
KHVGP
1956
VHVEA
1961
LTVPE
1966
EEKPS
1971
EPPTA
1976
TPEPP
1981
IKPRL
1986
GELTV
1991
TDATP
1996
DSLSL
2001
SWTVP
2006
EGQFD
2011
HFLVQ
2016
YRNGD
2021
GQPKA
2026
VRVPG
2031
HEEGV
2036
TISGL
2041
EPDHK
2046
YKMNL
2051
YGFHG
2056
GQRMG
2061
PVSVV
2066
GVTAA
2071
EEETP
2076
SPTEP
2081
SMEAP
2086
EPAEE
2091
PLLGE
2096
LTVTG
2101
SSPDS
2106
LSLSW
2111
TVPQG
2116
RFDSF
2121
TVQYK
2126
DRDGR
2131
PQVVR
2136
VGGEE
2141
SEVTV
2146
GGLEP
2151
GRKYK
2156
MHLYG
2161
LHEGR
2166
RVGPV
2171
SAVGV
2176
TAPEE
2181
ESPDA
2186
PLAKL
2191
RLGQM
2196
TVRDI
2201
TSDSL
2206
SLSWT
2211
VPEGQ
2216
FDHFL
2221
VQFKN
2226
GDGQP
2231
KAVRV
2236
PGHED
2241
GVTIS
2246
GLEPD
2251
HKYKM
2256
NLYGF
2261
HGGQR
2266
VGPVS
2271
AVGLT
2276
APGKD
2281
EEMAP
2286
ASTEP
2291
PTPEP
2296
PIKPR
2301
LEELT
2306
VTDAT
2311
PDSLS
2316
LSWTV
2321
PEGQF
2326
DHFLV
2331
QYKNG
2336
DGQPK
2341
ATRVP
2346
GHEDR
2351
VTISG
2356
LEPDN
2361
KYKMN
2366
LYGFH
2371
GGQRV
2376
GPVSA
2381
IGVTA
2386
AEEET
2391
PSPTE
2396
PSMEA
2401
PEPPE
2406
EPLLG
2411
ELTVT
2416
GSSPD
2421
SLSLS
2426
WTVPQ
2431
GRFDS
2436
FTVQY
2441
KDRDG
2446
RPQVV
2451
RVGGE
2456
ESEVT
2461
VGGLE
2466
PGRKY
2471
KMHLY
2476
GLHEG
2481
RRVGP
2486
VSTVG
2491
VTAPQ
2496
EDVDE
2501
TPSPT
2506
EPGTE
2511
APGPP
2516
EEPLL
2521
GELTV
2526
TGSSP
2531
DSLSL
2536
SWTVP
2541
QGRFD
2546
SFTVQ
2551
YKDRD
2556
GRPQA
2561
VRVGG
2566
QESKV
2571
TVRGL
2576
EPGRK
2581
YKMHL
2586
YGLHE
2591
GRRLG
2596
PVSAV
2601
GVTED
2606
EAETT
2611
QAVPT
2616
MTPEP
2621
PIKPR
2626
LGELT
2631
MTDAT
2636
PDSLS
2641
LSWTV
2646
PEGQF
2651
DHFLV
2656
QYRNG
2661
DGQPK
2666
AVRVP
2671
GHEDG
2676
VTISG
2681
LEPDH
2686
KYKMN
2691
LYGFH
2696
GGQRV
2701
GPISV
2706
IGVTA
2711
AEEET
2716
PSPTE
2721
LSTEA
2726
PEPPE
2731
EPLLG
2736
ELTVT
2741
GSSPD
2746
SLSLS
2751
WTIPQ
2756
GHFDS
2761
FTVQY
2766
KDRDG
2771
RPQVM
2776
RVRGE
2781
ESEVT
2786
VGGLE
2791
PGRKY
2796
KMHLY
2801
GLHEG
2806
RRVGP
2811
VSTVG
2816
VTEDE
2821
AETTQ
2826
AVPTT
2831
TPEPP
2836
NKPRL
2841
GELTV
2846
TDATP
2851
DSLSL
2856
SWMVP
2861
EGQFD
2866
HFLVQ
2871
YRNGD
2876
GQPKV
2881
VRVPG
2886
HEDGV
2891
TISGL
2896
EPDHK
2901
YKMNL
2906
YGFHG
2911
GQRVG
2916
PISVI
2921
GVTAA
2926
EEETP
2931
APTEP
2936
STEAP
2941
EPPEE
2946
PLLGE
2951
LTVTG
2956
SSPDS
2961
LSLSW
2966
TIPQG
2971
RFDSF
2976
TVQYK
2981
DRDGR
2986
PQVVR
2991
VRGEE
2996
SEVTV
3001
GGLEP
3006
GCKYK
3011
MHLYG
3016
LHEGQ
3021
RVGPV
3026
SAVGV
3031
TAPKD
3036
EAETT
3041
QAVPT
3046
MTPEP
3051
PIKPR
3056
LGELT
3061
VTDAT
3066
PDSLS
3071
LSWMV
3076
PEGQF
3081
DHFLV
3086
QYRNG
3091
DGQPK
3096
AVRVP
3101
GHEDG
3106
VTISG
3111
LEPDH
3116
KYKMN
3121
LYGFH
3126
GGQRV
3131
GPVSA
3136
IGVTE
3141
EETPS
3146
PTEPS
3151
TEAPE
3156
APEEP
3161
LLGEL
3166
TVTGS
3171
SPDSL
3176
SLSWT
3181
VPQGR
3186
FDSFT
3191
VQYKD
3196
RDGQP
3201
QVVRV
3206
RGEES
3211
EVTVG
3216
GLEPG
3221
RKYKM
3226
HLYGL
3231
HEGQR
3236
VGPVS
3241
TVGIT
3246
APLPT
3251
PLPVE
3256
PRLGE
3261
LAVAA
3266
VTSDS
3271
VGLSW
3276
TVAQG
3281
PFDSF
3286
LVQYR
3291
DAQGQ
3296
PQAVP
3301
VSGDL
3306
RAVAV
3311
SGLDP
3316
ARKYK
3321
FLLFG
3326
LQNGK
3331
RHGPV
3336
PVEAR
3341
TAPDT
3346
KPSPR
3351
LGELT
3356
VTDAT
3361
PDSVG
3366
LSWTV
3371
PEGEF
3376
DSFVV
3381
QYKDK
3386
DGRLQ
3391
VVPVA
3396
ANQRE
3401
VTVQG
3406
LEPSR
3411
KYRFL
3416
LYGLS
3421
GRKRL
3426
GPISA
3431
DSTTA
3436
PLEKE
3441
LPPHL
3446
GELTV
3451
AEETS
3456
SSLRL
3461
SWTVA
3466
QGPFD
3471
SFVVQ
3476
YRDTD
3481
GQPRA
3486
VPVAA
3491
DQRTV
3496
TVEDL
3501
EPGKK
3506
YKFLL
3511
YGLLG
3516
GKRLG
3521
PVSAL
3526
GMTAP
3531
EEDTP
3536
APELA
3541
PEAPE
3546
PPEEP
3551
RLGVL
3556
TVTDT
3561
TPDSM
3566
RLSWS
3571
VAQGP
3576
FDSFV
3581
VQYED
3586
TNGQP
3591
QALLV
3596
DGDQS
3601
KILIS
3606
GLEPS
3611
TPYRF
3616
LLYGL
3621
HEGKR
3626
LGPLS
3631
AEGTT
3636
GLAPA
3641
GQTSE
3646
ESRPR
3651
LSQLS
3656
VTDVT
3661
TSSLR
3666
LNWEA
3671
PPGAF
3676
DSFLL
3681
RFGVP
3686
SPSTL
3691
EPHPR
3696
PLLQR
3701
ELMVP
3706
GTRHS
3711
AVLRD
3716
LRSGT
3721
LYSLT
3726
LYGLR
3731
GPHKA
3736
DSIQG
3741
TARTL
3746
SPVLE
3751
SPRDL
3756
QFSEI
3761
RETSA
3766
KVNWM
3771
PPPSR
3776
ADSFK
3781
VSYQL
3786
ADGGE
3791
PQSVQ
3796
VDGQA
3801
RTQKL
3806
QGLIP
3811
GARYE
3816
VTVVS
3821
VRGFE
3826
ESEPL
3831
TGFLT
3836
TVPDG
3841
PTQLR
3846
ALNLT
3851
EGFAV
3856
LHWKP
3861
PQNPV
3866
DTYDV
3871
QVTAP
3876
GAPPL
3881
QAETP
3886
GSAVD
3891
YPLHD
3896
LVLHT
3901
NYTAT
3906
VRGLR
3911
GPNLT
3916
SPASI
3921
TFTTG
3926
LEAPR
3931
DLEAK
3936
EVTPR
3941
TALLT
3946
WTEPP
3951
VRPAG
3956
YLLSF
3961
HTPGG
3966
QNQEI
3971
LLPGG
3976
ITSHQ
3981
LLGLF
3986
PSTSY
3991
NARLQ
3996
AMWGQ
4001
SLLPP
4006
VSTSF
4011
TTGGL
4016
RIPFP
4021
RDCGE
4026
EMQNG
4031
AGASR
4036
TSTIF
4041
LNGNR
4046
ERPLN
4051
VFCDM
4056
ETDGG
4061
GWLVF
4066
QRRMD
4071
GQTDF
4076
WRDWE
4081
DYAHG
4086
FGNIS
4091
GEFWL
4096
GNEAL
4101
HSLTQ
4106
AGDYS
4111
MRVDL
4116
RAGDE
4121
AVFAQ
4126
YDSFH
4131
VDSAA
4136
EYYRL
4141
HLEGY
4146
HGTAG
4151
DSMSY
4156
HSGSV
4161
FSARD
4166
RDPNS
4171
LLISC
4176
AVSYR
4181
GAWWY
4186
RNCHY
4191
ANLNG
4196
LYGST
4201
VDHQG
4206
VSWYH
4211
WKGFE
4216
FSVPF
4221
TEMKL
4226
RPRNF
4231
RSPAG
4236
GG
4241
Mutation Information
DNA mutation:
None
Peptide Range:
3766 ~ 3790
Mut AA position:
3778 (13 in Wild Type peptide)
Alignment
Wild Type:
"RETSAKVNWMPPPSRADSFKVSYQL
||||||||||||.||||||||||||
Mutant:
RETSAKVNWMPPRSRADSFKVSYQL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TNXB
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay