Immunogenicity 9397

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PABPC4L
Transcript ID
NM_001114734
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (428 aa)
MRVLP
1
ELGES
6
CLNSI
11
AWPLC
16
GDPEA
21
STLEP
26
GQSCD
31
LVSPH
36
RDCSK
41
NSRGQ
46
THSGK
51
DKEMN
56
VAAKY
61
RMASL
66
YVGDL
71
HADVT
76
EDLLF
81
RKFST
86
VGPVL
91
SIRIC
96
RDQVT
101
RRSLG
106
YAYVN
111
FLQLA
116
DAQKA
121
LDTMN
126
FDIIK
131
GKSIR
136
LMWSQ
141
RDAYL
146
RRSGI
151
GNVFI
156
KNLDK
161
SIDNK
166
TLYEH
171
FSAFG
176
KILSS
181
KVMSD
186
DQGSK
191
GYAFV
196
HFQNQ
201
SAADR
206
AIEEM
211
NGKLL
216
KGCKV
221
FVGRF
226
KNRKD
231
REAEL
236
RSKAS
241
EFTNV
246
YIKNF
251
GGDMD
256
DERLK
261
DVFSK
266
YGKTL
271
SVKVM
276
TDSSG
281
KSKGF
286
GFVSF
291
DSHEA
296
AKKAV
301
EEMNG
306
RDING
311
QLIFV
316
GRAQK
321
KVERQ
326
AELKQ
331
MFEQL
336
KRERI
341
RGCQG
346
VKLYI
351
KNLDD
356
TIDDE
361
KLRNE
366
FSSFG
371
SISRV
376
KVMQE
381
EGQSK
386
GFGLI
391
CFSSP
396
EDATK
401
AMTEM
406
NGRIL
411
GSKPL
416
SIALA
421
QRH
426
Mutation Information
DNA mutation:
None
Peptide Range:
119 ~ 143
Mut AA position:
131 (13 in Wild Type peptide)
Alignment
Wild Type:
"LADAQKALDTMNFDIIKGKSIRLMW
||||||||||||.||||||||||||
Mutant:
LADAQKALDTMNVDIIKGKSIRLMW"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PABPC4L

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay