Immunogenicity 9422

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KBTBD13
Transcript ID
NM_001101362
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (458 aa)
MARGP
1
QTLVQ
6
VWVGG
11
QLFQA
16
DRALL
21
VEHCG
26
FFRGL
31
FRSGM
36
RETRA
41
AEVRL
46
GVLSA
51
GGFRA
56
TLQVL
61
RGDRP
66
ALAAE
71
DELLQ
76
AVECA
81
AFLQA
86
PALAR
91
FLEHN
96
LTSDN
101
CALLC
106
DAAAA
111
FGLRD
116
VFHSA
121
ALFIC
126
DGERE
131
LAAEL
136
ALPEA
141
RAYVA
146
ALRPS
151
SYAAV
156
STHTP
161
APGFL
166
EDASR
171
TLCYL
176
DEEED
181
AWRTL
186
AALPL
191
EASTL
196
LAGVA
201
TLGNK
206
LYIVG
211
GVRGA
216
SKEVV
221
ELGFC
226
YDPDG
231
GTWHE
236
FPSPH
241
QPRYD
246
TALAG
251
FDGRL
256
YAIGG
261
EFQRT
266
PISSV
271
ERYDP
276
AAGCW
281
SFVAD
286
LPQPA
291
AGVPC
296
AQACG
301
RLFVC
306
LWRPA
311
DTTAV
316
VEYAV
321
RTDAW
326
LPVAE
331
LRRPQ
336
SYGHC
341
MVAHR
346
DSLYV
351
VRNGP
356
SDDFL
361
HCAID
366
CLNLA
371
TGQWT
376
ALPGQ
381
FVNSK
386
GALFT
391
AVVRG
396
DTVYT
401
VNRMF
406
TLLYA
411
IEGGT
416
WRLLR
421
EKAGF
426
PRPGS
431
LQTFL
436
LRLPP
441
GAPGP
446
VTSTT
451
AEL
456
Mutation Information
DNA mutation:
None
Peptide Range:
48 ~ 72
Mut AA position:
60 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRLGVLSAGGFRATLQVLRGDRPAL
||||||||||||.||||||||||||
Mutant:
VRLGVLSAGGFRTTLQVLRGDRPAL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KBTBD13

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay