Immunogenicity 9467

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LYPLAL1
Transcript ID
NM_138794
HLA INFO
B*18:01
TCR INFO

No TCR info found!

T cell Tumor cell B*18:01
sequence
Full length protein sequence (237 aa)
MAAAS
1
GSVLQ
6
RCIVS
11
PAGRH
16
SASLI
21
FLHGS
26
GDSGQ
31
GLRMW
36
IKQVL
41
NQDLT
46
FQHIK
51
IIYPT
56
APPRS
61
YTPMK
66
GGISN
71
VWFDR
76
FKITN
81
DCPEH
86
LESID
91
VMCQV
96
LTDLI
101
DEEVK
106
SGIKK
111
NRILI
116
GGFSM
121
GGCMA
126
IHLAY
131
RNHQD
136
VAGVF
141
ALSSF
146
LNKAS
151
AVYQA
156
LQKSN
161
GVLPE
166
LFQCH
171
GTADE
176
LVLHS
181
WAEET
186
NSMLK
191
SLGVT
196
TKFHS
201
FPNVY
206
HELSK
211
TELDI
216
LKLWI
221
LTKLP
226
GEMEK
231
QK
236
Mutation Information
DNA mutation:
None
Peptide Range:
33 ~ 57
Mut AA position:
45 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGQGLRMWIKQVLNQDLTFQHIKII
||||||||||||.||||||||||||
Mutant:
SGQGLRMWIKQVVNQDLTFQHIKII"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LYPLAL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay