Immunogenicity 9496

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NRN1
Transcript ID
NM_001278711
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
sequence
Full length protein sequence (168 aa)
MATAA
1
RPQPD
6
HSSSA
11
PGLRT
16
SRLPS
21
FQRGG
26
RGCIR
31
GSHSE
36
YRVHA
41
YLVQA
46
VRAAG
51
KCDAV
56
FKGFS
61
DCLLK
66
LGDSM
71
ANYPQ
76
GLDDK
81
TNIKT
86
VCTYW
91
EDFHS
96
CTVTA
101
LTDCQ
106
EGAKD
111
MWDKL
116
RKESK
121
NLNIQ
126
GSLFE
131
LCGSG
136
NGAAG
141
SLLPA
146
FPVLL
151
VSLSA
156
ALATW
161
LSF
166
Mutation Information
DNA mutation:
None
Peptide Range:
9 ~ 33
Mut AA position:
21 (13 in Wild Type peptide)
Alignment
Wild Type:
"PDHSSSAPGLRTSRLPSFQRGGRGC
||||||||||||.||||||||||||
Mutant:
PDHSSSAPGLRTYRLPSFQRGGRGC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NRN1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay