Immunogenicity 9502

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TAS2R50
Transcript ID
NM_176890
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (299 aa)
MITFL
1
YIFFS
6
ILIMV
11
LFVLG
16
NFANG
21
FIALV
26
NFIDW
31
VKRKK
36
ISSAD
41
QILTA
46
LAVSR
51
IGLLW
56
ALLLN
61
WYLTV
66
LNPAF
71
YSVEL
76
RITSY
81
NAWVV
86
TNHFS
91
MWLAA
96
NLSIF
101
YLLKI
106
ANFSN
111
LLFLH
116
LKRRV
121
RSVIL
126
VILLG
131
TLIFL
136
VCHLL
141
VANMD
146
ESMWA
151
EEYEG
156
NMTGK
161
MKLRN
166
TVHLS
171
YLTVT
176
TLWSF
181
IPFTL
186
SLISF
191
LMLIC
196
SLCKH
201
LKKMQ
206
LHGEG
211
SQDLS
216
TKVHI
221
KALQT
226
LISFL
231
LLCAI
236
FFLFL
241
IVSVW
246
SPRRL
251
RNDPV
256
VMVSK
261
AVGNI
266
YLAFD
271
SFILI
276
WRTKK
281
LKHTF
286
LLILC
291
QIRC
296
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 18
Mut AA position:
6 (6 in Wild Type peptide)
Alignment
Wild Type:
"MITFLYIFFSILIMVLFVLGNFANG
|||||.||||||||||||
Mutant:
MITFLCIFFSILIMVLFV-------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TAS2R50

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay