Immunogenicity 9540

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GJC2
Transcript ID
NM_02043
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (439 aa)
MTNMS
1
WSFLT
6
RLLEE
11
IHNHS
16
TFVGK
21
VWLTV
26
LVVFR
31
IVLTA
36
VGGEA
41
IYSDE
46
QAKFT
51
CNTRQ
56
PGCDN
61
VCYDA
66
FAPLS
71
HVRFW
76
VFQIV
81
VISTP
86
SVMYL
91
GYAVH
96
RLARA
101
SEQER
106
RRALR
111
RRPGP
116
RRAPR
121
AHLPP
126
PHAGW
131
PEPAD
136
LGEEE
141
PMLGL
146
GEEEE
151
EEETG
156
AAEGA
161
GEEAE
166
EAGAE
171
EACTK
176
AVGAD
181
GKAAG
186
TPGPT
191
GQHDG
196
RRRIQ
201
REGLM
206
RVYVA
211
QLVAR
216
AAFEV
221
AFLVG
226
QYLLY
231
GFEVR
236
PFFPC
241
SRQPC
246
PHVVD
251
CFVSR
256
PTEKT
261
VFLLV
266
MYVVS
271
CLCLL
276
LNLCE
281
MAHLG
286
LGSAQ
291
DAVRG
296
RRGPP
301
ASAPA
306
PAPRP
311
PPCAF
316
PAAAA
321
GLACP
326
PDYSL
331
VVRAA
336
ERARA
341
HDQNL
346
ANLAL
351
QALRD
356
GAAAG
361
DRDRD
366
SSPCV
371
GLPAA
376
SRGPP
381
RAGAP
386
ASRTG
391
SATSA
396
GTVGE
401
QGRPG
406
THERP
411
GAKPR
416
AGSEK
421
GSASS
426
RDGKT
431
TVWI
436
Mutation Information
DNA mutation:
None
Peptide Range:
377 ~ 399
Mut AA position:
389 (13 in Wild Type peptide)
Alignment
Wild Type:
"LPAASRGPPRAGAPASRTGSATS
||||||||||||.||||||||||
Mutant:
LPAASRGPPRAGTPASRTGSATS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GJC2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay