Immunogenicity 9953

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
DNM1L
Transcript ID
ENST00000266481
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (699 aa)
MEALI
1
PVINK
6
LQDVF
11
NTVGA
16
DIIQL
21
PQIVV
26
VGTQS
31
SGKSS
36
VLESL
41
VGRDL
46
LPRGT
51
GIVTR
56
RPLIL
61
QLVHV
66
SQEDK
71
RKTTG
76
EENGV
81
EAEEW
86
GKFLH
91
TKNKL
96
YTDFD
101
EIRQE
106
IENET
111
ERISG
116
NNKGV
121
SPEPI
126
HLKIF
131
SPNVV
136
NLTLV
141
DLPGM
146
TKVPV
151
GDQPK
156
DIELQ
161
IRELI
166
LRFIS
171
NPNSI
176
ILAVT
181
AANTD
186
MATSE
191
ALKIS
196
REVDP
201
DGRRT
206
LAVIT
211
KLDLM
216
DAGTD
221
AMDVL
226
MGRVI
231
PVKLG
236
IIGVV
241
NRSQL
246
DINNK
251
KSVTD
256
SIRDE
261
YAFLQ
266
KKYPS
271
LANRN
276
GTKYL
281
ARTLN
286
RLLMH
291
HIRDC
296
LPELK
301
TRINV
306
LAAQY
311
QSLLN
316
SYGEP
321
VDDKS
326
ATLLQ
331
LITKF
336
ATEYC
341
NTIEG
346
TAKYI
351
ETSEL
356
CGGAR
361
ICYIF
366
HETFG
371
RTLES
376
VDPLG
381
GLNTI
386
DILTA
391
IRNAT
396
GPRPA
401
LFVPE
406
VSFEL
411
LVKRQ
416
IKRLE
421
EPSLR
426
CVELV
431
HEEMQ
436
RIIQH
441
CSNYS
446
TQELL
451
RFPKL
456
HDAIV
461
EVVTC
466
LLRKR
471
LPVTN
476
EMVHN
481
LVAIE
486
LAYIN
491
TKHPD
496
FADAC
501
GLMNN
506
NIEEQ
511
RRNRL
516
ARELP
521
SAVSR
526
DKVAS
531
GGGGV
536
GDGVQ
541
EPTTG
546
NWRGM
551
LKTSK
556
AEELL
561
AEEKS
566
KPIPI
571
MPASP
576
QKGHA
581
VNLLD
586
VPVPV
591
ARKLS
596
AREQR
601
DCEVI
606
ERLIK
611
SYFLI
616
VRKNI
621
QDSVP
626
KAVMH
631
FLVNH
636
VKDTL
641
QSELV
646
GQLYK
651
SSLLD
656
DLLTE
661
SEDMA
666
QRRKE
671
AADML
676
KALQG
681
ASQII
686
AEIRE
691
THLW
696
Mutation Information
DNA mutation:
None
Peptide Range:
95 ~ 119
Mut AA position:
107 (13 in Wild Type peptide)
Alignment
Wild Type:
"HTKNKLYTDFDEIRQEIENETERIS
||||||||||||.||||||||||||
Mutant:
HTKNKLYTDFDEVRQEIENETERIS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DNM1L

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay